[HTML][HTML] Biodegradable polymers as drug delivery systems for bone regeneration

K Aoki, N Saito - Pharmaceutics, 2020 - mdpi.com
Regenerative medicine has been widely researched for the treatment of bone defects. In the
field of bone regenerative medicine, signaling molecules and the use of scaffolds are of …

[HTML][HTML] Harvesting of autogenous bone graft from the ascending mandibular ramus compared with the chin region: a systematic review and meta-analysis focusing on …

T Starch-Jensen, D Deluiz, S Deb… - Journal of oral & …, 2020 - ncbi.nlm.nih.gov
Harvesting of Autogenous Bone Graft from the Ascending Mandibular Ramus Compared with
the Chin Region: a Systematic Review and Meta-Analysis Focusing on Complications and …

Regeneration of segmental defects in metatarsus of sheep with vascularized and customized 3D-printed calcium phosphate scaffolds

L Vidal, C Kampleitner, S Krissian, MA Brennan… - Scientific reports, 2020 - nature.com
Although autografts are considered to be the gold standard treatment for reconstruction of
large bone defects resulting from trauma or diseases, donor site morbidity and limited …

Chest-wall reconstruction with a customized titanium-alloy prosthesis fabricated by 3D printing and rapid prototyping

X Wen, S Gao, J Feng, S Li, R Gao, G Zhang - Journal of cardiothoracic …, 2018 - Springer
Background As 3D printing technology emerge, there is increasing demand for a more
customizable implant in the repair of chest-wall bony defects. This article aims to present a …

Craniofacial therapy: advanced local therapies from nano-engineered titanium implants to treat craniofacial conditions

K Gulati, C Ding, T Guo, H Guo, H Yu… - International Journal of …, 2023 - nature.com
Nano-engineering-based tissue regeneration and local therapeutic delivery strategies show
significant potential to reduce the health and economic burden associated with craniofacial …

[HTML][HTML] Ganoderal A effectively induces osteogenic differentiation of human amniotic mesenchymal stem cells via cross-talk between Wnt/β-catenin and BMP/SMAD …

YQ Wang, NX Wang, Y Luo, CY Yu, JH Xiao - Biomedicine & …, 2020 - Elsevier
Osteogenic inducers play central roles in effective stem cell-based treatment of bone
defects/losses. However, the current routine osteogenic inducer is a cocktail comprising …

Generation of rhBMP-2-induced juvenile ossicles in aged mice

K Dai, T Shen, Y Yu, S Deng, L Mao, J Wang, C Liu - Biomaterials, 2020 - Elsevier
Critical-sized bone defects and nonunions following fracture are common among elderly
patients and severely reduce the quality of life. Dysfunctional senescent endothelial and …

The use of electrospun organic and carbon nanofibers in bone regeneration

K Aoki, H Haniu, YA Kim, N Saito - Nanomaterials, 2020 - mdpi.com
There has been an increasing amount of research on regenerative medicine for the
treatment of bone defects. Scaffolds are needed for the formation of new bone, and various …

Bone-regeneration therapy using biodegradable scaffolds: Calcium phosphate bioceramics and biodegradable polymers

K Aoki, H Ideta, Y Komatsu, A Tanaka, M Kito… - Bioengineering, 2024 - mdpi.com
Calcium phosphate-based synthetic bone is broadly used for the clinical treatment of bone
defects caused by trauma and bone tumors. Synthetic bone is easy to use; however, its …

[HTML][HTML] Preparation and characterization of cockle shell aragonite nanocomposite porous 3D scaffolds for bone repair

SK Mahmood, MZAB Zakaria, ISBA Razak… - … and biophysics reports, 2017 - Elsevier
The demands for applicable tissue-engineered scaffolds that can be used to repair load-
bearing segmental bone defects (SBDs) is vital and in increasing demand. In this study …