The roles of FLOT1 in human diseases

Z Zhan, M Ye, X Jin - Molecular Medicine Reports, 2023 - spandidos-publications.com
FLOT1, a scaffold protein of lipid rafts, is involved in several biological processes, including
lipid raft protein‑dependent or clathrin‑independent endocytosis, and the formation of …

Molecular alterations in cutaneous squamous cell carcinoma in immunocompetent and immunosuppressed hosts—A systematic review

DA Tsang, SYC Tam, CC Oh - Cancers, 2023 - mdpi.com
Simple Summary Cutaneous squamous cell carcinoma (cSCC) is the second most common
form of skin cancer worldwide. Due to its high mutational burden, cSCC remains poorly …

Idiopathic male infertility is strongly associated with aberrant DNA methylation of imprinted loci in sperm: a case-control study

Q Tang, F Pan, J Yang, Z Fu, Y Lu, X Wu, X Han… - Clinical …, 2018 - Springer
Background Male infertility is a complex disease caused by a combination of genetic,
environmental, and lifestyle factors. Abnormal epigenetic programming has been proposed …

Reducing non‐melanoma skin cancer risk in renal transplant recipients

Z Thet, AK Lam, D Ranganathan, SY Aung, T Han… - …, 2021 - Wiley Online Library
With an increasing number of renal transplant recipients (RTRs) and improving patient
survival, a higher incidence of non‐melanoma skin cancer (NMSC) has been observed …

Epigenome-wide association study of prostate cancer in African Americans identifies DNA methylation biomarkers for aggressive disease

Y Xu, CW Tsai, WS Chang, Y Han, M Huang… - Biomolecules, 2021 - mdpi.com
DNA methylation plays important roles in prostate cancer (PCa) development and
progression. African American men have higher incidence and mortality rates of PCa than …

DNA hypo-methylation facilitates anti-inflammatory responses in severe ulcerative colitis

H Taman, CG Fenton, E Anderssen, J Florholmen… - PLoS …, 2021 - journals.plos.org
Severe ulcerative colitis (UC) is a potentially life-threatening disease with a potential
colorectal cancer (CRC) risk. The aim of this study was to explore the relationship between …

[HTML][HTML] Cutaneous squamous cell carcinoma arising in immunosuppressed patients: a systematic review of tumor profiling studies

ED Blue, SC Freeman, MB Lobl, DD Clarey… - JID innovations, 2022 - Elsevier
As solid organ transplantation becomes more prevalent, more individuals are living as
members of the immunosuppressed population with an elevated risk for cutaneous …

The applications of DNA methylation as a biomarker in kidney transplantation: a systematic review

I Cristoferi, TA Giacon, K Boer, M van Baardwijk… - Clinical …, 2022 - Springer
Background Although kidney transplantation improves patient survival and quality of life,
long-term results are hampered by both immune-and non-immune-mediated complications …

Unveiling the role of DNA methylation in kidney transplantation: novel perspectives toward biomarker identification

A Agodi, M Barchitta, A Maugeri… - BioMed Research …, 2019 - Wiley Online Library
The burden of chronic kidney disease is dramatically rising, making it a major public health
concern worldwide. Kidney transplantation is now the best treatment for patients with end …

Variations in DNA methylation and allograft rejection

K Boer, DA Hesselink, CC Baan - Current Opinion in Organ …, 2021 - journals.lww.com
Actual research publications on DNA methylation in relation to allograft rejection are scarce,
which makes it challenging to determine its potential clinical value. Extensive research is …