Sepsis is characterized as an uncontrolled host response to infection, and it represents a
serious health challenge, causing excess mortality and morbidity worldwide. The discovery …

Background Sepsis coincides with altered gene expression in different tissues.
Accumulating evidence has suggested that microRNAs, long non-coding RNAs, and circular …

Background Endothelial dysfunction plays a critical role in the development of sepsis-related
organ failure; however, the mechanisms that govern its development are not fully …

Objective Sepsis, as a disease affecting the microcirculation and tissue perfusion, results in
tissue hypoxia and multiple organ dysfunctions. Bone mesenchymal stem cell (BMSC) …

Introduction Septic cardiomyopathy is a common complication of sepsis with high morbidity
and mortality, but lacks specific therapy. This study aimed to reveal the role of circTLK1 and …

To investigate the mechanism of Schisandrin B (Sch B) on the inflammation in LPS-induced
sepsis. Sepsis mouse model was established by injecting LPS. qRT-PCR and western blot …

The excessive hospital mortality associated with acute respiratory distress syndrome
(ARDS) in adults mandates an urgent need for developing new therapies and tools for the …

Background The inflammatory response of macrophages is responsible for sepsis. Long
noncoding RNA nuclear enriched abundant transcript 1 (NEAT1) has been reported to be …

Aim of the study: Kaempferol is a flavonoid and important part of the diet. Kaempferol has
shown antioxidant, antiinflammatory and antidiabetic activities in various studies. However …

Ex vivo lung perfusion (EVLP) shows promise in ameliorating pretransplant acute lung injury
(ALI) and expanding the donor organ pool, but the mechanisms of ex vivo repair remain …