Aloe‐emodin: a review of its pharmacology, toxicity, and pharmacokinetics

X Dong, Y Zeng, Y Liu, L You, X Yin… - Phytotherapy …, 2020 - Wiley Online Library
Aloe‐emodin is a naturally anthraquinone derivative and an active ingredient of Chinese
herbs, such as Cassia occidentalis, Rheum palmatum L., Aloe vera, and Polygonum …

Review on the phytochemistry and toxicological profiles of Aloe vera and Aloe ferox

F Nalimu, J Oloro, I Kahwa, PE Ogwang - Future Journal of Pharmaceutical …, 2021 - Springer
Abstract Background Aloe vera and Aloe ferox have over the years been among the most
sought-after Aloe species in the treatment of ailments worldwide. This review provides …

Chrysophanol: a review of its pharmacology, toxicity and pharmacokinetics

L Xie, H Tang, J Song, J Long… - Journal of Pharmacy …, 2019 - academic.oup.com
Objective Chrysophanol is a natural anthraquinone, also known as chrysophanic acid and 1,
8-dihydroxy-3-methyl-anthraquinone. It has been widely used in the food and …

Potential therapeutic effects of curcumin mediated by JAK/STAT signaling pathway: a review

M Ashrafizadeh, H Rafiei… - Phytotherapy …, 2020 - Wiley Online Library
Curcumin is a naturally occurring nutraceutical compound with a number of therapeutic and
biological activities such as antioxidant, anti‐inflammatory, anti‐diabetic, antitumor, and …

Physcion and physcion 8-O-β-glucopyranoside: A review of their pharmacology, toxicities and pharmacokinetics

Y Liu, S Chu, S Yang, Y Peng, S Ren, B Wen… - Chemico-biological …, 2019 - Elsevier
Anthraquinones constitute an important class of natural and synthetic compounds with a
broad scope of pharmacological including anti-bacterial, antioxidant, laxative, anti-tumor …

[HTML][HTML] Hepatoprotection and hepatotoxicity of Chinese herb Rhubarb (Dahuang): How to properly control the “General (Jiang Jun)” in Chinese medical herb

T Zhuang, X Gu, N Zhou, L Ding, L Yang… - Biomedicine & …, 2020 - Elsevier
Abstract Chinese herb Rhubarb (Dahuang), one of the most widely used traditional Chinese
medicine in clinical application for over a thousand years and known as the “General (Jiang …

Aloe emodin induces hepatotoxicity by activating NF-κB inflammatory pathway and P53 apoptosis pathway in zebrafish

Y Quan, L Gong, J He, Y Zhou, M Liu, Z Cao, Y Li… - Toxicology letters, 2019 - Elsevier
The aim of this study was to investigate the hepatotoxic effect and its underlying mechanism
of aloe emodin (AE). AE was docked with the targets of NF-κB inflammatory pathway and …

The genus Cassia L.: Ethnopharmacological and phytochemical overview

M Khurm, X Wang, H Zhang, SN Hussain… - Phytotherapy …, 2021 - Wiley Online Library
Nature gifts medicinal plants with the untapped and boundless treasure of active chemical
constituents with significant therapeutic potential that makes these plants a beneficial source …

[HTML][HTML] Induction of apoptosis in HepaRG cell line by aloe-emodin through generation of reactive oxygen species and the mitochondrial pathway

X Dong, J Fu, X Yin, C Qu, C Yang, H He… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Aloe-emodin (1, 8-dihydroxy-3-hydroxymethyl-anthraquinone), an
anthraquinone active compounds, is isolated from some traditional medicinal plants such as …

Emodin induces apoptosis in human hepatocellular carcinoma HepaRG cells via the mitochondrial caspase‑dependent pathway

X Dong, B Ni, J Fu, X Yin, L You, X Leng… - Oncology …, 2018 - spandidos-publications.com
Emodin‑induced hepatotoxicity in vivo and in vitro has been gaining increasing attention.
However, the exact molecular pathways underlying these effects remain poorly clarified. The …