[HTML][HTML] Antioxidant, anti-inflammatory, anti-diabetic, and pro-osteogenic activities of polyphenols for the treatment of two different chronic diseases: type 2 diabetes …

ES Scarpa, A Antonelli, G Balercia, S Sabatelli… - Biomolecules, 2024 - mdpi.com
Polyphenols are natural bioactives occurring in medicinal and aromatic plants and food and
beverages of plant origin. Compared with conventional therapies, plant-derived …

Age-related bone diseases: Role of inflammaging

J Bi, C Zhang, C Lu, C Mo, J Zeng, M Yao, B Jia… - Journal of …, 2024 - Elsevier
Bone aging is characterized by an imbalance in the physiological and pathological
processes of osteogenesis, osteoclastogenesis, adipogenesis, and chondrogenesis …

[HTML][HTML] The role of polyphenols in modulating mitophagy: Implications for therapeutic interventions

X Lin, W Liu, X Hu, Z Liu, F Wang, J Wang - Pharmacological Research, 2024 - Elsevier
This review rigorously assesses the burgeoning research into the role of polyphenols in
modulating mitophagy, an essential cellular mechanism for the targeted removal of impaired …

Quercetin in the Prevention of Induced Periodontal Disease in Animal Models: A Systematic Review and Meta-Analysis

M Laky, M Arslan, X Zhu, X Rausch-Fan, A Moritz… - Nutrients, 2024 - mdpi.com
Background: Periodontitis is an inflammatory condition initiated by oral bacteria and is
associated with several systemic diseases. Quercetin is an anti-inflammatory and anti …

Polyphenol-based polymer nanoparticles for inhibiting amyloid protein aggregation: recent advances and perspectives

S Fang, K Zhang, D Liu, Y Yang, H Xi, W Xie… - Frontiers in …, 2024 - frontiersin.org
Polyphenols are a group of naturally occurring compounds that possess a range of
biological properties capable of potentially mitigating or preventing the progression of age …

[HTML][HTML] Molecular mechanism of Achyranthis bidentatae radix and Morindae officinalis radix in osteoporosis therapy: An investigation based on network …

J Wang, Y Huang, L Guo, J Li, S Zhou - Biochemistry and Biophysics …, 2023 - Elsevier
Objective To investigate the targets and mechanism of Achyranthis bidentatae radix and
Morindae officinalis radix (ABR-MOR) for the treatment of osteoporosis (OP) by utilizing …

Accessible and Effective Nanomedicines: Self‐Assembly Products From Chinese Herbal Medicines (CHMs)

YL Wang, Y Mu, YL Zhang, X Luo… - Advanced Functional …, 2024 - Wiley Online Library
The emergence of nanotechnology has significantly promoted the development of the
medical field, and the development of nanomedicines has broadened the application …

Urolithin B protects mice from diet-induced obesity, insulin resistance, and intestinal inflammation by regulating gut microbiota composition

P Chen, R Wang, J Lei, L Feng, B Zhou - Food & Function, 2024 - pubs.rsc.org
The increasing prevalence of obesity and type 2 diabetes (T2D) signifies the failure of
conventional treatments for these diseases. The gut microbiota has been proposed as a key …

Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies

V Das, JH Miller, CG Alladi, N Annadurai… - Medicinal Research …, 2024 - Wiley Online Library
As the world population ages, there will be an increasing need for effective therapies for
aging‐associated neurodegenerative disorders, which remain untreatable. Dementia due to …

Osmundacetone ameliorates Alzheimer's-like pathologies by inhibiting β-amyloid fibrillation, oxidative damage and neuroinflammation in APP/PS1 transgenic mice

LX Zhao, H Ren, JY Su, Q Zhang, DL He, TY Wu… - Phytomedicine, 2024 - Elsevier
Background β-Amyloid (Aβ) fibrillation is critical for Aβ deposition and cytotoxicity during the
progression of Alzheimer's disease (AD). Consequently, anti-Aβ monoclonal antibody drugs …