Regulation of fungal secondary metabolism

AA Brakhage - Nature Reviews Microbiology, 2013 - nature.com
Fungi produce a multitude of low-molecular-mass compounds known as secondary
metabolites, which have roles in a range of cellular processes such as transcription …

Fungal secondary metabolism—from biochemistry to genomics

NP Keller, G Turner, JW Bennett - Nature reviews microbiology, 2005 - nature.com
Much of natural product chemistry concerns a group of compounds known as secondary
metabolites. These low-molecular-weight metabolites often have potent physiological …

Metabolic gene clusters in eukaryotes

HW Nützmann, C Scazzocchio… - Annual Review of …, 2018 - annualreviews.org
In bacteria, more than half of the genes in the genome are organized in operons. In contrast,
in eukaryotes, functionally related genes are usually dispersed across the genome. There …

Bacterial volatile compounds: functions in communication, cooperation, and competition

T Netzker, EMF Shepherdson… - Annual Review of …, 2020 - annualreviews.org
Bacteria produce a multitude of volatile compounds. While the biological functions of these
deceptively simple molecules are unknown in many cases, for compounds that have been …

The evolution of fungal metabolic pathways

JH Wisecaver, JC Slot, A Rokas - PLoS genetics, 2014 - journals.plos.org
Fungi contain a remarkable range of metabolic pathways, sometimes encoded by gene
clusters, enabling them to digest most organic matter and synthesize an array of potent small …

Epigenetic Control of Effector Gene Expression in the Plant Pathogenic Fungus Leptosphaeria maculans

JL Soyer, M El Ghalid, N Glaser, B Ollivier… - PLoS …, 2014 - journals.plos.org
Plant pathogens secrete an arsenal of small secreted proteins (SSPs) acting as effectors that
modulate host immunity to facilitate infection. SSP-encoding genes are often located in …

Progress in tracing the evolutionary paths of cytochrome P450

DR Nelson - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2011 - Elsevier
The state of cytochrome P450 sequence accumulation in different phyla is summarized.
12,456 P450s are currently named, with about 6000 more that are known, but not yet …

Prototype of an intertwined secondary-metabolite supercluster

P Wiemann, CJ Guo, JM Palmer… - Proceedings of the …, 2013 - National Acad Sciences
The hallmark trait of fungal secondary-metabolite gene clusters is well established,
consisting of contiguous enzymatic and often regulatory gene (s) devoted to the production …

Enzymology and molecular biology of aflatoxin biosynthesis

RE Minto, CA Townsend - Chemical reviews, 1997 - ACS Publications
Enzymology and Molecular Biology of Aflatoxin Biosynthesis | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications …

Genetic improvement of processes yielding microbial products

JL Adrio, AL Demain - FEMS microbiology reviews, 2006 - academic.oup.com
Although microorganisms are extremely good in presenting us with an amazing array of
valuable products, they usually produce them only in amounts that they need for their own …