PLGA-based nanomedicine: history of advancement and development in clinical applications of multiple diseases
HO Alsaab, FD Alharbi, AS Alhibs, NB Alanazi… - Pharmaceutics, 2022 - mdpi.com
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …
Drug delivery systems based on polyethylene glycol hydrogels for enhanced bone regeneration
S Sun, Y Cui, B Yuan, M Dou, G Wang, H Xu… - … in bioengineering and …, 2023 - frontiersin.org
Drug delivery systems composed of osteogenic substances and biological materials are of
great significance in enhancing bone regeneration, and appropriate biological carriers are …
great significance in enhancing bone regeneration, and appropriate biological carriers are …
Reactive oxygen species (ROS): utilizing injectable antioxidative hydrogels and ROS-producing therapies to manage the double-edged sword
Reactive oxygen species (ROS) are generated in cellular metabolism and are essential for
cellular signalling networks and physiological functions. However, the functions of ROS are …
cellular signalling networks and physiological functions. However, the functions of ROS are …
[HTML][HTML] Polymer based sustained drug delivery to the ocular posterior segment: barriers and future opportunities for the treatment of neovascular pathologies
There is an increasing momentum in research and pharmaceutical industry communities to
design sustained, non-invasive delivery systems to treat chronic neovascular ocular …
design sustained, non-invasive delivery systems to treat chronic neovascular ocular …
Functional thermoresponsive hydrogel molecule to material design for biomedical applications
Temperature-induced, rapid changes in the viscosity and reproducible 3-D structure
formation makes thermos-sensitive hydrogels an ideal delivery system to act as a cell …
formation makes thermos-sensitive hydrogels an ideal delivery system to act as a cell …
The recent advancement in the PLGA-based thermo-sensitive hydrogel for smart drug delivery
F Rahmani, R Atabaki, S Behrouzi… - International Journal of …, 2023 - Elsevier
To date, hydrogels have opened new prospects for potential applications for drug delivery.
The thermo-sensitive hydrogels have the great potential to provide more effective and …
The thermo-sensitive hydrogels have the great potential to provide more effective and …
Ocular delivery of therapeutic proteins: a review
DH Shastri, AC Silva, H Almeida - Pharmaceutics, 2023 - mdpi.com
Therapeutic proteins, including monoclonal antibodies, single chain variable fragment
(ScFv), crystallizable fragment (Fc), and fragment antigen binding (Fab), have accounted for …
(ScFv), crystallizable fragment (Fc), and fragment antigen binding (Fab), have accounted for …
Optimization of an injectable hydrogel depot system for the controlled release of retinal-targeted hybrid nanoparticles
A drawback in the development of treatments that can reach the retina is the presence of
barriers in the eye that restrain compounds from reaching the target. Intravitreal injections …
barriers in the eye that restrain compounds from reaching the target. Intravitreal injections …
Neurotrophic factor-based pharmacological approaches in neurological disorders
M Alfonsetti, M d'Angelo, V Castelli - Neural regeneration …, 2023 - journals.lww.com
Aging is a physiological event dependent on multiple pathways that are linked to lifespan
and processes leading to cognitive decline. This process represents the major risk factor for …
and processes leading to cognitive decline. This process represents the major risk factor for …
Delivery systems in ocular retinopathies: the promising future of intravitreal hydrogels as sustained-release scaffolds
Slow-release delivery systems are needed to ensure long-term sustained treatments for
retinal diseases such as age-related macular degeneration and diabetic retinopathy, which …
retinal diseases such as age-related macular degeneration and diabetic retinopathy, which …