Mitochondria are dynamic organelles with multiple functions. They participate in necrotic cell
death and programmed apoptotic, and are crucial for cell metabolism and survival …

The COVID-19 pandemic caused by the coronavirus (SARS-CoV-2) has taken the world by
surprise into a major crisis of overwhelming morbidity and mortality. This highly infectious …

Accumulating evidence shows that oxidative stress plays an essential role in the
pathogenesis and progression of many diseases. The imbalance between the production of …

Geroscience, the new interdisciplinary field that aims to understand the relationship between
aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on …

Mitochondrial dynamics are regulated by two sets of opposed processes: mitochondrial
fusion and fission, and mitochondrial biogenesis and degradation (including mitophagy), as …

Background Inflammation and oxidative stress play critical roles in patients with chronic
obstructive pulmonary disease (COPD). Mitochondrial oxidative stress might be involved in …

The rise in life expectancy worldwide has been accompanied by an increased incidence of
age-related diseases, representing an enormous burden on healthcare services and …

Chronic obstructive pulmonary disease (COPD) includes chronic bronchitis and
emphysema. Environmental exposure, primarily cigarette smoking, can cause high oxidative …

Markers of oxidative stress are increased in chronic obstructive pulmonary disease (COPD)
and reactive oxygen species (ROS) are able to alter biological molecules, signaling …

Mitochondria are a distinguishing feature of eukaryotic cells. Best known for their critical
function in energy production via oxidative phosphorylation (OXPHOS), mitochondria are …