The role of enriched environment in neural development and repair
Y Han, M Yuan, YS Guo, XY Shen, ZK Gao… - Frontiers in cellular …, 2022 - frontiersin.org
In addition to genetic information, environmental factors play an important role in the
structure and function of nervous system and the occurrence and development of some …
structure and function of nervous system and the occurrence and development of some …
Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus
The decline of brain function during aging is associated with epigenetic changes, including
DNA methylation. Lifestyle interventions can improve brain function during aging, but their …
DNA methylation. Lifestyle interventions can improve brain function during aging, but their …
Longitudinal manganese‐enhanced magnetic resonance imaging of neural projections and activity
Manganese‐enhanced magnetic resonance imaging (MEMRI) holds exceptional promise
for preclinical studies of brain‐wide physiology in awake‐behaving animals. The objectives …
for preclinical studies of brain‐wide physiology in awake‐behaving animals. The objectives …
[HTML][HTML] Environmental enrichment leads to behavioral circadian shifts enhancing brain-wide functional connectivity between sensory cortices and eliciting increased …
Environmental enrichment induces widespread neuronal changes, but the initiation of the
cascade is unknown. We ascertained the critical period of divergence between …
cascade is unknown. We ascertained the critical period of divergence between …
Enhancement of astrocytic gap junctions Connexin43 coupling can improve long‐term isoflurane anesthesia–mediated brain network abnormalities and cognitive …
R Dong, P Lv, Y Han, L Jiang, Z Wang… - CNS Neuroscience …, 2022 - Wiley Online Library
Aim Astrocytes are connected by gap junctions Connexin43 (GJs‐Cx43) forming an
extensive intercellular network and maintain brain homeostasis. Perioperative …
extensive intercellular network and maintain brain homeostasis. Perioperative …
[HTML][HTML] Enriched environment treatment promotes neural functional recovery together with microglia polarization and remyelination after cerebral ischemia in rats
Y Han, X Shen, Z Gao, P Han, X Bi - Brain Research Bulletin, 2024 - Elsevier
Background Microglia activation and oligodendrocyte maturation are critical for
remyelination after cerebral ischemia. Studies have shown that enriched environment (EE) …
remyelination after cerebral ischemia. Studies have shown that enriched environment (EE) …
Development and advancements in rodent MRI-based brain atlases
X Ma, Y Xing, R Zhai, Y Du, H Yan - Heliyon, 2024 - cell.com
Rodents, particularly mice and rats, are extensively utilized in fundamental neuroscience
research. Brain atlases have played a pivotal role in this field, evolving from traditional …
research. Brain atlases have played a pivotal role in this field, evolving from traditional …
Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice
D Huang, Y Fan, J Zhang, Q Wang, M Ding, R Hou… - Experimental …, 2024 - Elsevier
Anxiety and depression are the most common mental health disorders worldwide, each
affecting around 30% stroke survivors. These complications not only affect the functional …
affecting around 30% stroke survivors. These complications not only affect the functional …
Phasic firing of dopaminergic neurons in the ventral tegmental area triggers peripheral immune responses
Dopaminergic neurons in the ventral tegmental area (VTA) play a crucial role in the
processing of reward-related information. Recent studies with pharmacological …
processing of reward-related information. Recent studies with pharmacological …
Cholecystokinin receptor antagonist challenge elicits brain-wide functional connectome modulation with micronetwork hippocampal decreased calcium transients
The cortical distribution and functional role of cholecystokinin (CCK) are largely unknown.
Here, a CCK receptor antagonist challenge paradigm was developed to assess functional …
Here, a CCK receptor antagonist challenge paradigm was developed to assess functional …