Many different regulatory mechanisms of renal fibrosis are known to date, and those related
to transforming growth factor-β1 (TGF-β1)-induced signaling have been studied in greater …

Liver fibrosis is the common outcome of many chronic liver diseases, resulting from altered
cell-cell and cell-matrix interactions that promote hepatic stellate cell (HSC) activation and …

Preeclampsia is a pregnancy-specific disease of high prevalence characterized by the onset
of hypertension, among other maternal or fetal signs. Its etiopathogenesis remains elusive …

STOX1 is a transcription factor that is implicated in the high prevalence of human gestational
diseases. It has been studied in various types of gestational diseases using different …

Background: Renal fibrosis is a common pathophysiological feature of chronic kidney
disease. Acute kidney injury (AKI) is defined as an independent causal factor of chronic …

Objectives The present study was designed to obverse the protection of patchouli alcohol
(PA) ameliorates hypertensive nephropathy in spontaneously hypertensive rats (SHR) and …

Therapeutic management of diabetic myocardial fibrosis remains an unsolved clinical
problem. Pin1, a peptidyl–prolyl isomerase, impacts diverse cellular processes and plays a …

Non-reversible fibrosis is common in various diseases such as chronic renal failure, liver
cirrhosis, chronic pancreatitis, pulmonary fibrosis, rheumatoid arthritis and atherosclerosis …

Abstract Background & aim Slit/Robo signaling was originally identified as a repulsive
guidance cue in regulating axon branching and neuronal migration. Hepatic stellate cells …

Background Fibroblasts activation-induced fibrosis can cause idiopathic pulmonary fibrosis
(IPF). Excessive activation of fibroblasts contributes to poor healing or severe visceral …