Defensins represent an evolutionary ancient family of antimicrobial peptides that play
diverse roles in human health and disease. Defensins are cationic cysteine-containing …

Variability in the susceptibility to infectious disease and its clinical manifestation can be
determined by variation in the environment and by genetic variation in the pathogen and the …

Hundreds of genes reside in structurally complex, poorly understood regions of the human
genome,,. One such region contains the three amylase genes (AMY2B, AMY2A and AMY1) …

Hundreds of copy number variants are complex and multi-allelic, in that they have many
structural alleles and have rearranged multiple times in the ancestors who contributed …

The controversy surrounding the findings that copy number variation, of the CCL3 encoding
genes, influences HIV-1 infection and disease progression has been in part attributed to the …

A community based cross sectional study was carried out in Arsi Zone to document the
pattern of utilization of antenatal care (ANC) and to investigate factors that affect women's …

Sub‐Saharan Africa has continued leading in prevalence and incidence of major infectious
disease killers such as HIV/AIDS, tuberculosis, and malaria. Epidemiological triad of …

Both α-and β-defensins have anti–human immunodeficiency virus activity. These defensins
achieve human immunodeficiency virus inhibition through a variety of mechanisms …

Copy number variation (CNV), where a segment of DNA differs in copy number between
different individuals, is an extensive and often underappreciated source of genetic variation …

While multiallelic copy number variation (mCNV) loci are a major component of genomic
variation, quantifying the individual copy number of a locus and defining genotypes is …