Cellulases and beyond: the first 70 years of the enzyme producer Trichoderma reesei

RH Bischof, J Ramoni, B Seiboth - Microbial cell factories, 2016 - Springer
More than 70 years ago, the filamentous ascomycete Trichoderma reesei was isolated on
the Solomon Islands due to its ability to degrade and thrive on cellulose containing fabrics …

Trichoderma Research in the Genome Era

PK Mukherjee, BA Horwitz… - Annual review of …, 2013 - annualreviews.org
Trichoderma species are widely used in agriculture and industry as biopesticides and
sources of enzymes, respectively. These fungi reproduce asexually by production of conidia …

Genetic engineering of Trichoderma reesei cellulases and their production

IS Druzhinina, CP Kubicek - Microbial biotechnology, 2017 - Wiley Online Library
Lignocellulosic biomass, which mainly consists of cellulose, hemicellulose and lignin, is the
most abundant renewable source for production of biofuel and biorefinery products. The …

The genomes of three uneven siblings: footprints of the lifestyles of three Trichoderma species

M Schmoll, C Dattenböck… - Microbiology and …, 2016 - Am Soc Microbiol
The genus Trichoderma contains fungi with high relevance for humans, with applications in
enzyme production for plant cell wall degradation and use in biocontrol. Here, we provide a …

Employment of the CRISPR/Cas9 system to improve cellulase production in Trichoderma reesei

S Pant, P Nag, A Ghati, D Chakraborty… - Biotechnology …, 2022 - Elsevier
Trichoderma reesei has been explored intensively in the laboratory and on an industrial
scale for its highly potent cellulase secretion machinery since its characterization over 70 …

Accelerating strain engineering in biofuel research via build and test automation of synthetic biology

J Zhang, Y Chen, L Fu, E Guo, B Wang, L Dai… - Current Opinion in …, 2021 - Elsevier
Highlights•The lack of predictive modeling limits biosystems design for biofuel production.•
Automation in build and test accelerates strain engineering for biofuel research.•Microplates …

Making recombinant proteins in filamentous fungi-are we expecting too much?

H Nevalainen, R Peterson - Frontiers in microbiology, 2014 - frontiersin.org
Hosts used for the production of recombinant proteins are typically high-protein secreting
mutant strains that have been selected for a specific purpose, such as efficient production of …

Cellulases for biomass degradation: comparing recombinant cellulase expression platforms

M Garvey, H Klose, R Fischer, C Lambertz… - Trends in …, 2013 - cell.com
Improvement of cellulase expression has the potential to change the nature of the biofuel
industry. Increasing the economic feasibility of cellulase systems would significantly broaden …

[HTML][HTML] Systems biological approaches towards understanding cellulase production by Trichoderma reesei

CP Kubicek - Journal of biotechnology, 2013 - Elsevier
Recent progress and improvement in “-omics” technologies has made it possible to study
the physiology of organisms by integrated and genome-wide approaches. This bears the …

Engineering of filamentous fungi for efficient conversion of lignocellulose: tools, recent advances and prospects

G Liu, Y Qu - Biotechnology Advances, 2019 - Elsevier
Filamentous fungi, as the main producers of lignocellulolytic enzymes in industry, need to be
engineered to improve the economy of large-scale lignocellulose conversion. Investigation …