Thyroid hormones (THs) play critical roles in the differentiation, growth, metabolism, and
physiological function of virtually all tissues. TH binds to receptors that are ligand …

Iodine is a micronutrient needed for the production of thyroid hormones, which regulate
metabolism, growth, and development. Iodine deficiency or excess may alter the thyroid …

Abstract Thyroid hormones (TH) 3, 5, 3′, 5'-tetraiodothyronine or thyroxine (T4) and 3, 5, 3'-
triiodothyronine (T3) contain iodine atoms as part of their structure, and their synthesis occur …

Active iodide (I−) transport in both the thyroid and some extrathyroidal tissues is mediated by
the Na+/I− symporter (NIS). In the thyroid, NIS-mediated I− uptake plays a pivotal role in …

Abstract The Na+/I− symporter (NIS) is the plasma membrane glycoprotein that mediates
active I− transport in the thyroid and other tissues, such as salivary glands, stomach …

Abstract The Na+/I− symporter (NIS) is an integral plasma membrane glycoprotein that
mediates active I− transport into the thyroid follicular cells, the first step in thyroid hormone …

The sodium/glucose cotransporter family (SLCA5) has 220 or more members in animal and
bacterial cells. There are 11 human genes expressed in tissues ranging from epithelia to the …

The resurgence of the clinical use of perchlorate as a means of controlling amiodarone-
induced thyroid dysfunction has suggested a need for a more careful examination of the …

There are three families of glucose transporters in the human genome, SLC2, SLC5 and
SLC50. Here I review the structure and function of the SLC5 and SLC50 genes. The human …

Glucose enters eucaryotic cells via 2 different types of membrane associated carrier
proteins, the Na+‐coupled glucose transporters (SGLT) and glucose transporter facilitators …