Abstract This chapter summarizes methods for the synthesis of polypeptides by ring-opening
polymerization. Traditional and recently improved methods used to polymerize α-amino acid …

This article summarizes recent developments in the synthesis of polypeptides and hybrid
peptide copolymers. Traditional methods used to polymerize α-amino acid-N …

Small interfering RNAs (siRNAs) of 19− 25 bp mediate the cleavage of complementary
mRNA, leading to post-transcriptional gene silencing. We examined cationic lipid (CL) …

Self-assembly and self-organisation represent powerful tools for the programmed
generation of supramolecular materials with well-defined structures. 1 They involve the …

Cancer is an extremely complex disease, typically caused by mutations in cancer-critical
genes. By delivering therapeutic nucleic acids (NAs) to patients, gene therapy offers the …

Cationic liposomes (CLs) are used as nonviral vectors in worldwide human clinical trials of
gene therapy. Among other advantages, lipid–DNA complexes have the ability to transfer …

Lipids, the building blocks of cells, common to every living organisms, have the propensity to
self-assemble into well-defined structures over short and long-range spatial scales. The …

Didodecyldimethylammonium bromide (DDAB) lipid bilayer-protected gold nanoparticles
(AuNPs), which were stable and hydrophilic, were synthesized by in situ reduction of …

Understanding the delivery dynamics of nucleic acid nanocarriers is fundamental to improve
their design for therapeutic applications. We investigated the carrier structure–function …

Poly-γ-glutamic acid (γ-PGA) is a natural polymer composed of glutamic acid monomer and
it has garnered substantial attention in both the fields of material science and biomedicine …