Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations of the
GLA gene that result in a deficiency of the enzymatic activity of α-galactosidase A and …

Fabry disease (FD) is a rare, X-linked inherited disorder of glycosphingolipid metabolism. It
leads to the progressive accumulation of globotriaosylceramide within lysosomes due to a …

Background There is limited evidence on the risk stratification of cardiovascular outcomes in
patients with Fabry disease (FD). Objectives This study sought to classify FD patients into …

Background Enzyme replacement therapy (ERT) slows disease progression of Fabry
disease (FD), especially when initiated before the onset of irreversible organ damage …

Background The cardiac manifestations of Fabry disease are the leading cause of death, but
risk stratification remains inadequate. Identifying patients who are at risk of adverse cardiac …

Anderson-Fabry disease (AFD) is an X-linked lysosomal storage disorder caused by
deficient activity of the enzyme alpha-galactosidase. While AFD is recognized as a …

The restrictive cardiomyopathies constitute a heterogeneous group of myocardial diseases
with a different pathogenesis and overlapping clinical presentations. Diagnosing them …

Fabry disease (FD) is a genetic lysosomal storage disease with frequent cardiovascular
involvement, whose presence is a major determinant of adverse clinical outcomes. As a …

Aims Cardiomyopathy in Fabry disease (FD) is a major determinant of morbidity and
mortality. This study investigates the effects of FD-specific treatment using enzyme …

As a slowly progressive form of hypertrophic cardiomyopathy (HCM), Anderson-Fabry
disease (FD) resembles the phenotype of the most common sarcomeric forms, although …