Valvular heart diseases (VHDs) are currently treated using either mechanical or
bioprosthetic heart valves. Unfortunately, mechanical valves require lifelong anticoagulation …

Sterilization is the process of killing all microorganisms, while disinfection is the process of
killing or removing all kinds of pathogenic microorganisms except bacterial spores …

Cardiovascular diseases are the leading cause of global mortality. Over the past two
decades, researchers have tried to provide novel solutions for end-stage heart failure to …

Extracellular matrix (ECM) structure and biochemistry provide cell-instructive cues that
promote and regulate tissue growth, function, and repair. From a structural perspective, the …

Abstract Based on Organ Procurement and Transplantation Network data as of December
2019, more than 113 000 patients require an organ transplantation, yet, over the course of …

The tissue-engineered heart valve portends a new era in the field of valve replacement.
Decellularized heart valves are of great interest as a scaffold for the tissue-engineered heart …

The use of bioprostheses for heart valve therapy has gradually evolved over several
decades and both surgical and transcatheter devices are now highly successful. The rapid …

Tissue-engineered heart valve (TEHV) has emerged as a prospective alternative to
conventional valve prostheses. The decellularized heart valve (DHV) represents a promising …

Objective Acellular matrices of different allogeneic or xenogeneic origins are widely used as
structural scaffolds in regenerative medicine. The main goal of this research was to optimize …

The clinical use of decellularized cardiac valve allografts is increasing. Long‐term data will
be required to determine whether they outperform conventional cryopreserved allografts …