Antimicrobial Peptide Cec4 Eradicates Multidrug-Resistant Acinetobacter baumannii in vitro and in vivo

J Peng, Y Wang, Z Wu, C Mao, L Li, H Cao… - Drug Design …, 2023 - Taylor & Francis
Introduction Acinetobacter baumannii has become a major difficulty in the treatment of
bacteria-associated infection. The previously reported antimicrobial peptide Cec4 exhibited …

Molecular basis for substrate transport of Mycobacterium tuberculosis ABC importer DppABCD

T Hu, X Yang, Y Zhu, F Liu, X Yang, Z Xiong… - Science …, 2024 - science.org
The type I adenosine 5′-triphosphate (ATP)–binding cassette (ABC) transporter DppABCD
is believed to be responsible for the import of exogenous heme as an iron source into the …

Adaptive laboratory evolution and transcriptomics‐guided engineering of Escherichia coli for increased isobutanol tolerance

YS Jang, J Yang, JK Kim, TI Kim, YC Park… - Biotechnology …, 2024 - Wiley Online Library
As a renewable energy from biomass, isobutanol is considered as a promising alternative to
fossil fuels. To biotechnologically produce isobutanol, strain development using industrial …

The role of cytokines and pattern recognition receptors in inflammation caused by helicobacter pylori infection in gastric cancer

A Ganjali, BA Fakheri, A Bahari… - … Journal of Basic …, 2022 - ijbsm.zbmu.ac.ir
One of the most common and most critical mortality causes in modern society is
gastrointestinal (GI) cancer. Helicobacter pylori is one of the most potent risk factors of …

[HTML][HTML] Biophysical analysis of the Mycobacteria tuberculosis peptide binding protein DppA reveals a stringent peptide binding pocket

DM Fernando, CT Gee, EC Griffith, CJ Meyer, LA Wilt… - Tuberculosis, 2022 - Elsevier
The peptide binding protein DppA is an ABC transporter found in prokaryotes that has the
potential to be used as drug delivery tool for hybrid antibiotic compounds. Understanding the …

High variation across E. coli hybrid isolates identified in metabolism-related biological pathways co-expressed with virulent genes

R Gomes, A Denison Kroschel, S Day, R Jansen - Gut microbes, 2023 - Taylor & Francis
Virulent genes present in Escherichia coli (E. coli) can cause significant human diseases.
These enteropathogenic E. coli (EPEC) and enterotoxigenic E. coli (ETEC) isolates with …

[HTML][HTML] Genetic and Transcriptomic Variations for Amoxicillin Resistance in Helicobacter pylori under Cryopreservation

X Han, Y Zhang, L He, R Fan, L Sun, D Fan, Y Gong… - Pathogens, 2021 - mdpi.com
Some amoxicillin-resistant strains of H. pylori show a sharp decrease in amoxicillin
resistance after freezing. In China, most clinical gastric mucosal specimens are frozen and …

The transcriptome response of Enterobacter sp. S-33 is modulated by low pH-stress

K Kumari, PK Sharma, RP Singh - Genes & Genomics, 2024 - Springer
Background Acidic environments naturally occur worldwide and uncontrolled use of
agricultural practices may also cause acidification of soils. The development of acidic …