Hydrogel interfaces for merging humans and machines

H Yuk, J Wu, X Zhao - Nature Reviews Materials, 2022 - nature.com
The last few decades have witnessed unprecedented convergence between humans and
machines that closely operate around the human body. Despite these advances, traditional …

[HTML][HTML] Engineering the next generation of cell-based therapeutics

CJ Bashor, IB Hilton, H Bandukwala… - Nature Reviews Drug …, 2022 - nature.com
Cell-based therapeutics are an emerging modality with the potential to treat many currently
intractable diseases through uniquely powerful modes of action. Despite notable recent …

[HTML][HTML] The evolution of commercial drug delivery technologies

AM Vargason, AC Anselmo, S Mitragotri - Nature biomedical …, 2021 - nature.com
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …

Engineering living therapeutics with synthetic biology

A Cubillos-Ruiz, T Guo, A Sokolovska… - Nature Reviews Drug …, 2021 - nature.com
The steadfast advance of the synthetic biology field has enabled scientists to use genetically
engineered cells, instead of small molecules or biologics, as the basis for the development …

[HTML][HTML] Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes

NJ Hogrebe, M Ishahak, JR Millman - Cell Stem Cell, 2023 - cell.com
The generation of islet-like endocrine clusters from human pluripotent stem cells (hPSCs)
has the potential to provide an unlimited source of insulin-producing β cells for the treatment …

[HTML][HTML] Preparation of alginate-based biomaterials and their applications in biomedicine

H Zhang, J Cheng, Q Ao - Marine Drugs, 2021 - mdpi.com
Alginates are naturally occurring polysaccharides extracted from brown marine algae and
bacteria. Being biocompatible, biodegradable, non-toxic and easy to gel, alginates can be …

Polysaccharide hydrogels: Functionalization, construction and served as scaffold for tissue engineering

Q Yang, J Peng, H Xiao, X Xu, Z Qian - Carbohydrate Polymers, 2022 - Elsevier
Polysaccharide hydrogels have been widely utilized in tissue engineering. They interact with
the organismal environments, modulating the cargos release and realizing of long-term …

Dealing with the foreign‐body response to implanted biomaterials: strategies and applications of new materials

D Zhang, Q Chen, C Shi, M Chen, K Ma… - Advanced Functional …, 2021 - Wiley Online Library
Foreign‐body response caused by implanted biomaterials seriously impedes the function of
implants and is a major obstacle to the development of implantable biomaterials and …

Current status of alginate in drug delivery

DM Hariyadi, N Islam - Advances in pharmacological and …, 2020 - Wiley Online Library
Alginate is one of the natural polymers that are often used in drug‐and protein‐delivery
systems. The use of alginate can provide several advantages including ease of preparation …

Machine learning‐driven biomaterials evolution

A Suwardi, FK Wang, K Xue, MY Han, P Teo… - Advanced …, 2022 - Wiley Online Library
Biomaterials is an exciting and dynamic field, which uses a collection of diverse materials to
achieve desired biological responses. While there is constant evolution and innovation in …