The immune checkpoint blockade therapy has completely transformed cancer treatment
modalities because of its unprecedented and durable clinical responses in various cancers …

Immunogenic cell death (ICD) has aroused widespread attention because it can reconstruct
a tumor microenvironment and activate antitumor immunity. This study proposes a two‐way …

Immune checkpoint blockade (ICB) therapy revolutionized cancer treatment, but many
patients with impaired MHC-I expression remain refractory. Here, we combined FACS-based …

In recent years' development in nanotechnology utilization of DNA barcodes with potential
benefit of nanoparticulate system is a hallmark for novel advancement in healthcare …

Background Immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of
many cancers. However, the limited population that benefits from ICI therapy makes it …

Background Genetic information is becoming more readily available and is increasingly
being used to predict patient cancer types as well as their subtypes. Most classification …

Immunogenic cell death (ICD) induced by calcium ion (Ca2+) overload has attracted
significant attention owing to its ability to activate the immune system and generate durable …

Background Polyamines metabolism is closely related to tumor development and
progression, as well as tumor microenvironment (TME). In this study, we focused on …

Designing effective nanomedicines to induce durable anti-tumor immunity represents a
promising strategy for improving moderate immune stimulation. In this study, we engineered …

Immunotherapy initially demonstrated promising results in prostate cancer (PCa), but the
modest or negative results of many recent trials highlight the need to overcome the poor …