Over the past 10 years, circulating tumor cells (CTC) and circulating tumor DNA (ctDNA)
have received enormous attention as new biomarkers and subjects of translational research …

During the past ten years, circulating tumour cells (CTCs) have received enormous attention
as new biomarkers and the subject of basic research. Although CTCs are already used in …

Purpose: A method for enumerating circulating tumor cells (CTC) has received regulatory
clearance. The primary objective of this prospective study was to establish the relationship …

Ultrasensitive methods have been recently developed to detect circulating tumour cells
(CTCs) in the peripheral blood and disseminated tumour cells (DTCs) in the bone marrow …

Metastases are the most common cause of cancer-related death in patients with solid
tumors.[1–4] A considerable body of evidence indicates that tumor cells are shed from a …

Liquid biopsy is a new diagnostic concept that provides important information for monitoring
and identifying tumor genomes in body fluid samples. Detection of tumor origin …

Most cancer deaths are caused by haematogenous metastatic spread and subsequent
growth of tumour cells at distant organs. Disseminating tumour cells present in the …

Solid tumors derived from epithelial tissues (carcinomas) are responsible for 90% of all new
cancers in Europe, and the main four tumor entities are breast, prostate, lung, and colon …

Genomic technologies offer the promise of a comprehensive understanding of cancer.
These technologies are being used to characterize tumours at the molecular level, and …

Early spread of tumor cells is usually undetected by current imaging technologies. In
patients with cancer and no signs of overt metastases sensitive methods have been …