Cadmium is a heavy metal, which is widely used in industry, affecting human health through
occupational and environmental exposure. In mammals, it exerts multiple toxic effects and …

Cellular stress elicited by the toxic metal Cd 2+ does not coerce the cell into committing to
die from the onset. Rather, detoxification and adaptive processes are triggered concurrently …

The past decade has seen an intense focus on mechanisms of apoptosis. Many important
observations on the various signaling pathways mediating apoptotic cell death have been …

Cadmium (Cd) is an environmental pollutant of global concern with a 10–30‐year biological
half‐life in humans. Accumulating evidence suggests that the lung is one of the major target …

In various mammalian cells, two group IIb metals, cadmium and zinc, induce several
morphological and biochemical effects that are salient features of programmed cell death. In …

In this study, we tested the hypothesis that cadmium-induced developmental toxicity was
mediated via ectopic occurrence of apoptosis during embryonic development. We employed …

To investigate the underlying mechanism of neurotoxicity of cadmium, we examined the
effects of intraperitoneal injection of cadmium on messenger RNA (mRNA) expression of Bcl …

Cadmium is a well-known carcinogenic and immunotoxic metal commonly found in cigarette
smoke and industrial effluent. An altered intracellular calcium ([Ca2+] i) level has been …

In this study, BRL 3A cells were treated with different Cd concentrations (0, 10, 20, and 40
μmol/L) for 12 h and preincubated with or without N‐acetyl‐L‐cysteine (NAC)(2 mmol/L) for …

Previous reports have demonstrated that cadmium (Cd) may induce cell death via apoptosis,
but the mechanism responsible for cellular death is not clear. In this study, we investigated …