Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis

Y Han, J Byun, C Zhu, R Sun, JY Roh… - Nature …, 2023 - nature.com
Primary sclerosing cholangitis (PSC) is a rare autoimmune bile duct disease that is strongly
associated with immune-mediated disorders. In this study, we implemented multitrait joint …

Systematic review with meta-analysis: the impact of co-occurring immune-mediated inflammatory diseases on the disease course of inflammatory bowel diseases

M Attauabi, M Zhao, F Bendtsen… - Inflammatory Bowel …, 2021 - academic.oup.com
Abstract Background and Aims Patients with inflammatory bowel diseases (IBDs) are at risk
of developing a variety of other immune-mediated inflammatory diseases (IMIDs). The …

Cigarette smoking and risk of celiac disease: a systematic review and meta-analysis

K Wijarnpreecha, S Lou… - United European …, 2018 - journals.sagepub.com
Background/Objectives A negative association between cigarette smoking and celiac
disease has been observed but results were inconsistent across the published studies. A …

Alterations of the salivary and fecal microbiome in patients with primary sclerosing cholangitis

Y Lapidot, A Amir, S Ben-Simon, E Veitsman… - Hepatology …, 2021 - Springer
Background Primary sclerosing cholangitis (PSC) is a chronic, progressive liver disease
known for its frequent concurrence with inflammatory bowel disease. PSC can progress to …

Unique phenotypic characteristics and clinical course in patients with ulcerative colitis and primary sclerosing cholangitis: a multicenter US experience

MH Wang, OY Mousa, JJ Friton… - Inflammatory bowel …, 2020 - academic.oup.com
Introduction Ulcerative colitis (UC) associated with primary sclerosing cholangitis (PSC) is a
rare phenotype. We aimed to assess patients with UC-PSC or UC alone and describe …

Systematic replication of smoking disease associations using survey responses and EHR data in the All of Us Research Program

DJ Schlueter, L Sulieman, H Mo… - Journal of the …, 2024 - academic.oup.com
Abstract Objective The All of Us Research Program (All of Us) aims to recruit over a million
participants to further precision medicine. Essential to the verification of biobanks is a …

Genetic risk scores identify genetic aetiology of inflammatory bowel disease phenotypes

MD Voskuil, LM Spekhorst… - Journal of Crohn's …, 2021 - academic.oup.com
Abstract Background and Aims Inflammatory bowel disease [IBD] phenotypes are very
heterogeneous between patients, and current clinical and molecular classifications do not …

[HTML][HTML] Low prevalence of primary sclerosing cholangitis in patients with inflammatory bowel disease in India

A Singh, V Midha, V Narang, S Kedia… - Intestinal …, 2023 - synapse.koreamed.org
Methods Database of IBD patients at 5 tertiary care IBD centers in India were analyzed
retrospectively. Data were extracted and the prevalence of PSC-IBD was calculated. Results …

Einfluss des Rauchens auf den Gastrointestinaltrakt

S Popp, T Mang, M Scharitzer - Die Radiologie, 2022 - Springer
Hintergrund Nikotin ist ein hochwirksames Suchtgift, das bei regelmäßiger Einnahme
chronische oder unheilbare Erkrankungen und somit eine eingeschränkte Lebensqualität …

Influence of smoking on the gastrointestinal tract: Range of findings

S Popp, T Mang, M Scharitzer - Radiologie (Heidelberg, Germany), 2022 - europepmc.org
Background Nicotine is a highly addictive drug that, if consumed regularly, can result in
chronic or incurable diseases and a reduced quality of life. Objectives The aim of this review …