Natural products (NPs) are a significant source of inspiration towards the discovery of new
bioactive compounds based on novel molecular scaffolds. However, there are currently only …

Pseudo‐natural products (PNPs) combine natural product (NP) fragments in novel
arrangements not accessible by current biosynthesis pathways. As such they can be …

Natural products (NPs) inspire the design and synthesis of novel biologically relevant
chemical matter, for instance through biology‐oriented synthesis (BIOS). However, BIOS is …

Covering: up to 2020 Natural products (NPs) provide inspiration for the design of biologically
active compounds and libraries. In this review, we cover several experimental and in silico …

Bioactive compound design based on natural product (NP) structure may be limited because
of partial coverage of NP‐like chemical space and biological target space. These limitations …

Through evolution, nature has provided natural products (NPs) as a rich source of diverse
bioactive material. Many drug discovery programs have used nature as an inspiration for the …

In phenotypic compound discovery, conclusive identification of cellular targets and mode of
action are often impaired by off-target binding. In particular, microtubules are frequently …

Natural product (NP) structures are a rich source of inspiration for the discovery of new
biologically relevant chemical matter. In natural product inspired pseudo‐NPs, NP‐derived …

Covering: 2013–2022. Chemical diversification of natural products is an efficient way to
generate natural product-like compounds for modern drug discovery programs. Utilizing ring …

Abstract Pseudo‐natural‐product (NP) design combines natural product fragments to
provide unprecedented NP‐inspired compounds not accessible by biosynthesis, but …