Despite the enthusiasm surrounding novel targeted agents and immunotherapies,
chemotherapy remains the mainstay treatment for most human malignancies, either alone or …

Abstract G-CSF and GM-CSF are used widely to promote the production of granulocytes or
APCs. The US Food and Drug Administration approved G-CSF (filgrastim) for the treatment …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Neutrophils are the first responders to infection and injury and are critical for antimicrobial
host defense. Through the generation of reactive oxidants, activation of granular constituents …

Neutropenic colitis is a severe condition usually affecting immunocompromised patients. Its
exact pathogenesis is not completely understood. The main elements in disease onset …

An estimated 22 350 patients had multiple myeloma diagnosed in 2013, representing 1.3%
of all new cancers; 10 710 deaths are projected, representing 1.8% of cancer deaths …

Zusammenfassung Der Einsatz multimodaler Therapiekonzepte für urologische
Tumorerkrankungen konfrontiert den Urologen zunehmend mit den Nebenwirkungen der …

Background Chemotherapy-induced febrile neutropenia (FN) is a clinically important
complication that affects patient outcome by delaying chemotherapy doses or reducing dose …

How I diagnose and treat neutropenia : Current Opinion in Hematology How I diagnose and
treat neutropenia : Current Opinion in Hematology Log in or Register Subscribe to journalSubscribe …

Carfilzomib, a selective proteasome inhibitor approved in the USA in 2012, is a single agent
for relapsed and refractory multiple myeloma. Carfilzomib is administered as a 2–10-minute …