Physiology of astroglia
A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
The emerging nature of astrocyte diversity
BS Khakh, B Deneen - Annual review of neuroscience, 2019 - annualreviews.org
Astrocytes are morphologically complex, ubiquitous cells that are viewed as a
homogeneous population tiling the entire central nervous system (CNS). However, this view …
homogeneous population tiling the entire central nervous system (CNS). However, this view …
Making sense of astrocytic calcium signals—from acquisition to interpretation
A Semyanov, C Henneberger, A Agarwal - Nature Reviews …, 2020 - nature.com
Astrocytes functionally interact with neurons and with other brain cells. Although not
electrically excitable, astrocytes display a complex repertoire of intracellular Ca2+ signalling …
electrically excitable, astrocytes display a complex repertoire of intracellular Ca2+ signalling …
Astrocyte heterogeneity: impact to brain aging and disease
I Matias, J Morgado, FCA Gomes - Frontiers in aging neuroscience, 2019 - frontiersin.org
Astrocytes, one of the largest glial cell population in the central nervous system (CNS), play
a key function in several events of brain development and function, such as synapse …
a key function in several events of brain development and function, such as synapse …
Astrocyte calcium signaling: the third wave
N Bazargani, D Attwell - Nature neuroscience, 2016 - nature.com
The discovery that transient elevations of calcium concentration occur in astrocytes, and
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
Diversity of astrocyte functions and phenotypes in neural circuits
BS Khakh, MV Sofroniew - Nature neuroscience, 2015 - nature.com
Astrocytes tile the entire CNS. They are vital for neural circuit function, but have traditionally
been viewed as simple, homogenous cells that serve the same essential supportive roles …
been viewed as simple, homogenous cells that serve the same essential supportive roles …
Chemical landscape for tissue clearing based on hydrophilic reagents
K Tainaka, TC Murakami, EA Susaki, C Shimizu… - Cell reports, 2018 - cell.com
We describe a strategy for developing hydrophilic chemical cocktails for tissue delipidation,
decoloring, refractive index (RI) matching, and decalcification, based on comprehensive …
decoloring, refractive index (RI) matching, and decalcification, based on comprehensive …
Transient opening of the mitochondrial permeability transition pore induces microdomain calcium transients in astrocyte processes
Astrocytes extend highly branched processes that form functionally isolated microdomains,
facilitating local homeostasis by redistributing ions, removing neurotransmitters, and …
facilitating local homeostasis by redistributing ions, removing neurotransmitters, and …
Gliotransmission: beyond black-and-white
I Savtchouk, A Volterra - Journal of Neuroscience, 2018 - Soc Neuroscience
Astrocytes are highly complex cells with many emerging putative roles in brain function. Of
these, gliotransmission (active information transfer from glia to neurons) has probably the …
these, gliotransmission (active information transfer from glia to neurons) has probably the …
The role of astrocyte‐mediated plasticity in neural circuit development and function
NA Perez-Catalan, CQ Doe, SD Ackerman - Neural development, 2021 - Springer
Neuronal networks are capable of undergoing rapid structural and functional changes called
plasticity, which are essential for shaping circuit function during nervous system …
plasticity, which are essential for shaping circuit function during nervous system …