Protein arginine methylation in mammals: who, what, and why
MT Bedford, SG Clarke - Molecular cell, 2009 - cell.com
The covalent marking of proteins by methyl group addition to arginine residues can promote
their recognition by binding partners or can modulate their biological activity. A small family …
their recognition by binding partners or can modulate their biological activity. A small family …
Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential
CD Krause, ZH Yang, YS Kim, JH Lee, JR Cook… - Pharmacology & …, 2007 - Elsevier
Protein arginine N-methylation is a post-translational modification whose influence on cell
function is becoming widely appreciated. Protein arginine methyltransferases (PRMT) …
function is becoming widely appreciated. Protein arginine methyltransferases (PRMT) …
Human protein arginine methyltransferase 7 (PRMT7) is a type III enzyme forming ω-NG-monomethylated arginine residues
CI Zurita-Lopez, T Sandberg, R Kelly… - Journal of Biological …, 2012 - ASBMB
Full-length human protein arginine methyltransferase 7 (PRMT7) expressed as a fusion
protein in Escherichia coli was initially found to generate only ω-N G-monomethylated …
protein in Escherichia coli was initially found to generate only ω-N G-monomethylated …
The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans
SS Wolf - Cellular and molecular life sciences, 2009 - Springer
Abstract Information about the family of protein arginine methyltransferases (PRMTs) has
been growing rapidly over the last few years and the emerging role of arginine methylation …
been growing rapidly over the last few years and the emerging role of arginine methylation …
Protein arginine methylation: Cellular functions and methods of analysis
S Pahlich, RP Zakaryan, H Gehring - … et Biophysica Acta (BBA)-Proteins and …, 2006 - Elsevier
During the last few years, new members of the growing family of protein arginine
methyltransferases (PRMTs) have been identified and the role of arginine methylation in …
methyltransferases (PRMTs) have been identified and the role of arginine methylation in …
[HTML][HTML] Protein arginine methylation/demethylation and cancer
C Poulard, L Corbo, M Le Romancer - Oncotarget, 2016 - ncbi.nlm.nih.gov
Protein arginine methylation is a common post-translational modification involved in
numerous cellular processes including transcription, DNA repair, mRNA splicing and signal …
numerous cellular processes including transcription, DNA repair, mRNA splicing and signal …
High mobility group (HMG) proteins: Modulators of chromatin structure and DNA repair in mammalian cells
R Reeves - DNA repair, 2015 - Elsevier
It has been almost a decade since the last review appeared comparing and contrasting the
influences that the different families of High Mobility Group proteins (HMGA, HMGB and …
influences that the different families of High Mobility Group proteins (HMGA, HMGB and …
Interplay between chromatin remodelers and protein arginine methyltransferases
S Pal, S Sif - Journal of cellular physiology, 2007 - Wiley Online Library
Chromatin modifying enzymes have emerged as key regulators of all DNA based processes,
which control cell growth, development, and differentiation. Recently, it has become clear …
which control cell growth, development, and differentiation. Recently, it has become clear …
Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor
M Neault, FA Mallette, G Vogel… - Nucleic acids …, 2012 - academic.oup.com
Arginine methylation of histones is a well-known regulator of gene expression. Protein
arginine methyltransferase 6 (PRMT6) has been shown to function as a transcriptional …
arginine methyltransferase 6 (PRMT6) has been shown to function as a transcriptional …
Identification and characterization of the methyl arginines in the fragile X mental retardation protein Fmrp
A Stetler, C Winograd, J Sayegh… - Human molecular …, 2006 - academic.oup.com
Fragile X syndrome is the most common form of inherited mental retardation and is caused
by the absence of expression of the FMR1 gene. The protein encoded by this gene, Fmrp, is …
by the absence of expression of the FMR1 gene. The protein encoded by this gene, Fmrp, is …