[HTML][HTML] Nanomaterials for photo-based diagnostic and therapeutic applications

JU Menon, P Jadeja, P Tambe, K Vu, B Yuan… - Theranostics, 2013 - ncbi.nlm.nih.gov
Photo-based diagnosis and treatment methods are gaining prominence due to increased
spatial imaging resolution, minimally invasive modalities involved as well as localized …

A review of UHMWPE wear-induced osteolysis: the role for early detection of the immune response

AM Kandahari, X Yang, KA Laroche, AS Dighe, D Pan… - Bone research, 2016 - nature.com
In a world where increasing joint arthroplasties are being performed on increasingly
younger patients, osteolysis as the leading cause of failure after total joint arthroplasty (TJA) …

Development of macromolecular prodrug for rheumatoid arthritis

F Yuan, L Quan, L Cui, SR Goldring, D Wang - Advanced drug delivery …, 2012 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease that is considered to be one of
the major public health problems worldwide. The development of therapies that target tumor …

Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes

L Quan, Y Zhang, BJ Crielaard, A Dusad, SM Lele… - ACS …, 2014 - ACS Publications
As an emerging research direction, nanomedicine has been increasingly utilized to treat
inflammatory diseases. In this head-to-head comparison study, four established …

Thermoresponsive polymeric dexamethasone prodrug for arthritis pain

G Zhao, R Ren, X Wei, Z Jia, N Chen, Y Sun… - Journal of Controlled …, 2021 - Elsevier
Abstract Intra-articular (IA) glucocorticoids (GC) are commonly used for clinical management
of both osteoarthritis and rheumatoid arthritis, but their efficacy is limited by the relatively …

Nanomedicines for improved targetability to inflamed synovium for treatment of rheumatoid arthritis: multi-functionalization as an emerging strategy to optimize …

G Fang, Q Zhang, Y Pang, HE Thu, Z Hussain - Journal of Controlled …, 2019 - Elsevier
Owing to its intricate autoimmune pathophysiology and significant risks of progression to
other rheumatic co-morbidities (ie, osteoporosis and osteoarthritis), a plausible therapeutic …

Dexamethasone conjugates: Synthetic approaches and medical prospects

NV Dubashynskaya, AN Bokatyi, YA Skorik - Biomedicines, 2021 - mdpi.com
Dexamethasone (DEX) is the most commonly prescribed glucocorticoid (GC) and has a
wide spectrum of pharmacological activity. However, steroid drugs like DEX can have …

Inflammation-targeted delivery of celastrol via neutrophil membrane-coated nanoparticles in the management of acute pancreatitis

X Zhou, X Cao, H Tu, ZR Zhang… - Molecular …, 2019 - ACS Publications
Celastrol (CLT)-loaded PEG–PLGA nanoparticles (NPs/CLT) coated with neutrophil
membranes (NNPs/CLT) were explored for the management of acute pancreatitis (AP). PEG …

Poly (N-(2-hydroxypropyl) methacrylamide)-based nanotherapeutics

BS Tucker, BS Sumerlin - Polymer Chemistry, 2014 - pubs.rsc.org
This mini-review provides a brief overview of recent advances in the area of biologically-
relevant nanomaterials composed of poly (N-(2-hydroxypropyl) methacrylamide)(PHPMA) …

Statins, bone metabolism and treatment of bone catabolic diseases

Y Zhang, AD Bradley, D Wang, RA Reinhardt - Pharmacological research, 2014 - Elsevier
The discovery that statins had bone anabolic properties initiated many investigations into
their use for treatment of bone catabolic diseases, such as osteoporosis. This paper reviews …