Benefiting from the impressive increase in fundamental knowledge, the last 20 years have
shown a continuous burst of new ideas and consequently a plethora of new catalytic …

The development of synthetic methods for the introduction of the fluorine atom and
fluoroalklyl groups into organic molecules has gained increased attention. Synthetic organic …

The enantioselective functionalization of ubiquitous C (sp 3)–H bonds is ideally suited for
the construction of three-dimensional chiral structures. However, organic molecules often …

Metalloradical catalysis (MRC) exploits the metal-centred radicals present in open-shell
metal complexes as one-electron catalysts for the generation of metal-stabilized organic …

The catalytic dicarbofunctionalization of unsaturated π bonds represents a powerful platform
for the rapid construction of complex motifs. Despite remarkable progress, novel and efficient …

Atom transfer radical addition (ATRA) reactions are linchpin transformations in synthetic
chemistry enabling the atom-economic difunctionalization of alkenes. Thereby a rich …

Copper-catalyzed enantioselective coupling has been widely investigated, which allows
rapid construction of various chiral molecules. Despite important advances via polar and …

In contrast with the well-established enantioconvergent radical C (sp 3)–C cross-coupling of
racemic secondary alkyl electrophiles, the corresponding coupling of tertiary electrophiles to …

The direct functionalization of C (sp3)–H bonds represents one of the most investigated
approaches to develop new synthetic methodology. Among the available strategies for …

Chiral indole derivatives such as indolines and indolenines are important heterocyclic
frameworks which constitute the core structures of many natural products and bioactive …