Label-free microfluidic cell sorting and detection for rapid blood analysis

N Lu, HM Tay, C Petchakup, L He, L Gong, KK Maw… - Lab on a Chip, 2023 - pubs.rsc.org
Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …

A review on intelligent impedance cytometry systems: Development, applications and advances

T Tang, T Julian, D Ma, Y Yang, M Li, Y Hosokawa… - Analytica Chimica …, 2023 - Elsevier
Impedance cytometry is a well-established technique for counting and analyzing single
cells, with several advantages, such as convenience, high throughput, and no labeling …

Machine learning empowered multi-stress level electromechanical phenotyping for high-dimensional single cell analysis

M Liang, Q Tang, J Zhong, Y Ai - Biosensors and Bioelectronics, 2023 - Elsevier
Microfluidics provides a powerful platform for biological analysis by harnessing the ability to
precisely manipulate fluids and microparticles with integrated microsensors. Here, we …

Efficient bioparticle extraction using a miniaturized inertial microfluidic centrifuge

Y Fang, S Zhu, W Cheng, Z Ni, N Xiang - Lab on a Chip, 2022 - pubs.rsc.org
Conventional bioparticle extraction requires labor-intensive operation, and expensive and
bulky centrifuges. Herein, we report a miniaturized centrifuge by cascading four paralleled …

Acoustic quasi-periodic bioassembly based diverse stem cell arrangements for differentiation guidance

X Gao, X Hu, D Yang, Q Hu, J Zheng, S Zhao, C Zhu… - Lab on a Chip, 2023 - pubs.rsc.org
Arrangement patterns and geometric cues have been demonstrated to influence cell
function and fate, which calls for efficient and versatile cell patterning techniques. Despite …

Label-free multidimensional bacterial characterization with an ultrawide detectable concentration range by microfluidic impedance cytometry

J Chen, J Zhong, H Lei, Y Ai - Lab on a Chip, 2023 - pubs.rsc.org
Rapid and accurate identification of bacteria is of great importance to public health in
various fields, including medical diagnostics, food safety, and environmental monitoring …

Accurate profiling of blood components in microliter with position-insensitive coplanar electrodes-based cytometry

J Zhong, Q Tang, M Liang, Y Ai - Sensors and Actuators B: Chemical, 2022 - Elsevier
Differentiating and counting blood cell subtypes are essential for medical diagnosis.
Microfluidic impedance-based cytometry has been discussed in the past decade as cost …

Performance-enhanced clogging-free viscous sheath constriction impedance flow cytometry

J Zhu, Y Feng, H Chai, F Liang, Z Cheng, W Wang - Lab on a Chip, 2023 - pubs.rsc.org
As a label-free and high-throughput single cell analysis platform, impedance flow cytometry
(IFC) suffers from clogging caused by a narrow microchannel as mechanical constriction …

High‐throughput Raman‐activated cell sorting in the fingerprint region

M Lindley, J Gala de Pablo, W Peterson… - Advanced Materials …, 2022 - Wiley Online Library
Cell sorting is the workhorse of biological research and medicine. Cell sorters are commonly
used to sort heterogeneous cell populations based on their intrinsic features. Raman …

Assessment of the electrical penetration of cell membranes using four-frequency impedance cytometry

T Tang, X Liu, Y Yuan, T Zhang, R Kiya… - Microsystems & …, 2022 - nature.com
The electrical penetration of the cell membrane is vital for determining the cell interior via
impedance cytometry. Herein, we propose a method for determining the conductivity of the …