Sonic hedgehog (Shh) is well known as the molecule responsible for the induction and
maintenance of ventral neural tube structures. Recent data have shown that ventral …

Fibroblast growth factor (Fgf) signaling plays important roles in various developmental
processes including brain development. Here, we identified zebrafish fgf22 predominantly …

BACKGROUND Nine transcription factors comprise the PAX gene family that regulate
organogenesis. The urogenital system of PAX2 null male mice fails to develop properly …

Advances in neuroimaging techniques for the in vivo study of brain development have
expanded the understanding of normal and abnormal cerebellar development in the high …

Parkinson s disease (PD) is characterized by progressive degeneration of dopaminergic
(DA) neurons residing in the substantia nigra and innervating the straitum. Current medical …

Epilepsy is one of the most common neurological disorders, affecting about 1% of human
population worldwide. Epilepsy is characterized by the repeated occurrence of sudden …

La tesis¿ Role of DYRK1A in the development of the cerebral cortex. Implication in Down
Syndrome¿ se compone de los siguientes apartados: introducción de los conceptos básicos …

The main pathological hallmark in Parkinson's disease (PD) is the progressive loss of
dopaminergic (DA) neurons in the substantia nigra (SN), affecting movements such as …

The trigeminal subnucleus caudalis (Vc), which has been designated as the “medullary
dorsal horn”-analogous to the spinal dorsal horn (DH), relays noxious input from the …

Patched ist im Shh-Signaltransduktionsweg verantwortlich für die Ausbildung verschiedener
Organsysteme. Hier wurde, durch die Assoziation von Ptch mit dem BCNS und …