Interleukin-1β is a potential therapeutic target for periodontitis: a narrative review
R Cheng, Z Wu, M Li, M Shao, T Hu - International journal of oral …, 2020 - nature.com
Abstract Interleukin (IL)-1β, a pro-inflammatory cytokine, was elevated and participates in
periodontitis. Not only the link between IL-1β and periodontitis was proved by clinical …
periodontitis. Not only the link between IL-1β and periodontitis was proved by clinical …
Inflammatory mediators in osteoarthritis: A critical review of the state-of-the-art, current prospects, and future challenges
Osteoarthritis (OA) has traditionally been defined as a prototypical non-inflammatory
arthropathy, but today there is compelling evidence to suggest that it has an inflammatory …
arthropathy, but today there is compelling evidence to suggest that it has an inflammatory …
Exosomes derived from miR-92a-3p-overexpressing human mesenchymal stem cells enhance chondrogenesis and suppress cartilage degradation via targeting …
G Mao, Z Zhang, S Hu, Z Zhang, Z Chang… - Stem cell research & …, 2018 - Springer
Background WNT5A is known to be involved in the pathogenesis of osteoarthritis. This study
investigated the molecular mechanism of exosomal miR-92a-3p and WNT5A in …
investigated the molecular mechanism of exosomal miR-92a-3p and WNT5A in …
Inhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritis
Z Chen, H Zhong, J Wei, S Lin, Z Zong, F Gong… - Arthritis research & …, 2019 - Springer
Introduction Osteoarthritis (OA) is an inflammatory disease of the joints that causes
progressive disability in the elderly. Reactive oxygen species (ROS) play an important role …
progressive disability in the elderly. Reactive oxygen species (ROS) play an important role …
Exosomes derived from platelet-rich plasma administration in site mediate cartilage protection in subtalar osteoarthritis
Y Zhang, X Wang, J Chen, D Qian, P Gao, T Qin… - Journal of …, 2022 - Springer
Subtalar osteoarthritis (STOA) is often secondary to chronic ankle sprains, which seriously
affects the quality of life of patients. Due to its etiology and pathogenesis was not studied …
affects the quality of life of patients. Due to its etiology and pathogenesis was not studied …
[HTML][HTML] Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytes
F Zhou, J Mei, X Han, H Li, S Yang, M Wang… - … Pharmaceutica Sinica B, 2019 - Elsevier
The objective was to investigate the effect of kinsenoside (Kin) treatments on macrophage
polarity and evaluate the resulting protection of chondrocytes to attenuate osteoarthritis (OA) …
polarity and evaluate the resulting protection of chondrocytes to attenuate osteoarthritis (OA) …
Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
M Kapoor, J Martel-Pelletier, D Lajeunesse… - Nature Reviews …, 2011 - nature.com
Osteoarthritis (OA) is associated with cartilage destruction, subchondral bone remodeling
and inflammation of the synovial membrane, although the etiology and pathogenesis …
and inflammation of the synovial membrane, although the etiology and pathogenesis …
Proteases involved in cartilage matrix degradation in osteoarthritis
L Troeberg, H Nagase - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2012 - Elsevier
Osteoarthritis is a common joint disease for which there are currently no disease-modifying
drugs available. Degradation of the cartilage extracellular matrix is a central feature of the …
drugs available. Degradation of the cartilage extracellular matrix is a central feature of the …
[HTML][HTML] Circulating levels of IL-6 and TNF-α are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults
O Stannus, G Jones, F Cicuttini… - Osteoarthritis and …, 2010 - Elsevier
OBJECTIVE: The role of inflammation in osteoarthritis (OA) pathogenesis is unclear, and the
associations between inflammatory cytokines and cartilage loss have not been reported. We …
associations between inflammatory cytokines and cartilage loss have not been reported. We …