Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

Despite advances in surgery and adjuvant therapy, brain tumors represent one of the
leading causes of cancer‐related mortality and morbidity in both adults and children …

Glioma grading and classification, today based on histological features, is not always easy
to interpret and diagnosis partly relies on the personal experience of the neuropathologists …

Regardless of the significant progress made in surgical techniques and adjuvant therapies,
brain tumors are a major contributor to cancer-related morbidity and mortality in both …

Nuclear magnetic resonance spectroscopy (called NMR for ex vivo techniques and MRS for
in vivo techniques) has become a useful analytical and diagnostic tool in biomedicine. In the …

According to World Health Organization (WHO) estimates, cancer is responsible for more
deaths than all coronary heart disease or stroke worldwide, serving as a major public health …

BACKGROUND: Magnetic Resonance Imaging (MRI) nowadays plays an important role in
the evaluation of posterior fossa brain tumours in children for appropriate diagnosis …

We present here a novel surface mass spectrometry strategy to perform untargeted
metabolite profiling of formalin-fixed paraffin-embedded pediatric ependymoma archives …

Medulloblastoma is a frequent high-grade neoplasm among pediatric brain tumours. Its
classical imaging features are a midline tumour growing into the fourth ventricle, hyperdense …

High‐resolution magic angle spinning (HRMAS) MRS is a powerful method for gaining
insight into the physiological and pathological processes of cellular metabolism. Given its …