Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Biofilms: formation, research models, potential targets, and methods for prevention and treatment

Y Su, JT Yrastorza, M Matis, J Cusick, S Zhao… - Advanced …, 2022 - Wiley Online Library
Due to the continuous rise in biofilm‐related infections, biofilms seriously threaten human
health. The formation of biofilms makes conventional antibiotics ineffective and dampens …

Biofilms in diabetic foot ulcers: significance and clinical relevance

C Pouget, C Dunyach-Remy, A Pantel, S Schuldiner… - Microorganisms, 2020 - mdpi.com
Foot infections are the main disabling complication in patients with diabetes mellitus. These
infections can lead to lower-limb amputation, increasing mortality and decreasing the quality …

[PDF][PDF] IWGDF guidance on the diagnosis and management of foot infections in persons with diabetes

BA Lipsky, J Aragón-Sánchez, M Diggle… - Diabetes Metab Res …, 2016 - aogp.com.au
23. Do not select a specific type of dressing for a diabetic foot infection with the aim of
preventing an infection or improving its outcome (strong; high). 24. For diabetic foot …

Chronic wound infections: the role of Pseudomonas aeruginosa and Staphylococcus aureus

R Serra, R Grande, L Butrico, A Rossi… - Expert review of anti …, 2015 - Taylor & Francis
Chronic leg ulcers affect 1–2% of the general population and are related to increased
morbidity and health costs. Staphylococcus aureus and Pseudomonas aeruginosa are the …

Biofilms in diabetic foot ulcers: impact, risk factors and control strategies

AC Afonso, D Oliveira, MJ Saavedra, A Borges… - International journal of …, 2021 - mdpi.com
Diabetic foot ulcers (DFUs) are a serious complication from diabetes mellitus, with a huge
economic, social and psychological impact on the patients' life. One of the main reasons why …

Immunomodulatory biomaterials and their application in therapies for chronic inflammation-related diseases

JR Nakkala, Z Li, W Ahmad, K Wang, C Gao - Acta Biomaterialia, 2021 - Elsevier
The degree of tissue injuries such as the level of scarring or organ dysfunction, and the
immune response against them primarily determine the outcome and speed of healing …

Applications of bacteriophages in the treatment of localized infections in humans

VV Morozova, VV Vlassov, NV Tikunova - Frontiers in microbiology, 2018 - frontiersin.org
In the recent years, multidrug-resistant bacteria have become a global threat, and phage
therapy may to be used as an alternative to antibiotics or, at least, as a supplementary …

The role of the microbiome in nonhealing diabetic wounds

LR Kalan, MB Brennan - Annals of the New York Academy of …, 2019 - Wiley Online Library
Wound healing is a highly coordinated and complex process, and there can be devastating
consequences if it is interrupted. It is believed that, in combination with host factors …

Current concepts for the evaluation and management of diabetic foot ulcers

AF Mavrogenis, PD Megaloikonomos… - EFORT open …, 2018 - eor.bioscientifica.com
The lifetime risk for diabetic patients to develop a diabetic foot ulcer (DFU) is 25%. In these
patients, the risk of amputation is increased and the outcome deteriorates. More than 50% of …