Pattern-recognition receptors in endometriosis: A narrative review

B Guo, J Chen, J Zhang, Y Fang, X Liu… - Frontiers in …, 2023 - frontiersin.org
Endometriosis is closely associated with ectopic focal inflammation and immunosuppressive
microenvironment. Multiple types of pattern recognition receptors (PRRs) are present in the …

The nano-revolution in the diagnosis and treatment of endometriosis

C Volpini, N Bloise, M Dominoni, F Barra, VG Vellone… - Nanoscale, 2023 - pubs.rsc.org
Endometriosis is a painful gynecological disease with a high prevalence, affecting millions
of women worldwide. Innovative, non-invasive treatments, and new patient follow-up …

SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals

YK Lin, YY Li, Y Li, DJ Li, XL Wang, L Wang… - Frontiers in …, 2022 - frontiersin.org
Background Endometriosis (EMS), an endocrine-related inflammatory disease, is
characterized by estrogen and progesterone imbalance in ectopic lesions. However, its …

Hyaluronic acid-modified nanoplatforms as a vector for targeted delivery of autophagy-related gene to the endometriotic lesions in mice

M Zhao, M Zhang, Q Yu, W Fei, T Li, L Zhu… - … in Bioengineering and …, 2022 - frontiersin.org
This investigation probed endometriosis treatment using targeted nanoparticles (NPs) to
modulate autophagic activity. To that end, a novel form of polymer-based NP gene delivery …

CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis

J Tan, T Xu, Y Gou, H Wang, Z Liang, Y Cao… - Stem Cell Research & …, 2022 - Springer
Abstract Background Endometriosis (EMs) is a common benign gynecological disease that
affects approximately 10% of females of reproductive age. Endometriosis ectopic lesions …

miR‑143‑3p inhibits endometriotic stromal cell proliferation and invasion by inactivating autophagy in endometriosis

H Yang, T Hu, P Hu, C Qi… - Molecular medicine …, 2021 - spandidos-publications.com
Endometriosis (EM) is a multifactorial and debilitating chronic benign gynecological disease,
but the pathogenesis of the disease is not completely understood. Dysregulated expression …

Lipoxin A4 depresses inflammation and promotes autophagy via AhR/mTOR/AKT pathway to suppress endometriosis

ZX Huang, XR He, XY Ding, JH Chen… - American Journal of …, 2023 - Wiley Online Library
Background Endometriosis is a benign gynecological disease with the feature of estrogen
dependence and inflammation. The function of autophagy and the correlation with …

Role of autophagy in the pathogenesis and regulation of pain

G Zheng, J Ren, L Shang, Y Bao - European Journal of Pharmacology, 2023 - Elsevier
Pain is a ubiquitous and highly concerned clinical symptom, usually caused by peripheral or
central nervous injury, tissue damage, or other diseases. The long-term existence of pain …

Identification and analysis of potential autophagy-related biomarkers in endometriosis by WGCNA

J Wang, S Cong, H Wu, Y He, X Liu, L Sun… - Frontiers in molecular …, 2021 - frontiersin.org
Background: Endometriosis is a serious gynecological disorder characterized by debilitating
pain, infertility and the establishment of innervated endometriosis lesions outside the uterus …

Luoshi Neiyi Prescription inhibits estradiol synthesis and inflammation in endometriosis through the HIF1A/EZH2/SF-1 pathway

L Wu, D Lan, B Sun, R Su, F Pei, Z Kuang, Y Su… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Endometriosis (EMS) is a common gynecological disease
that causes dysmenorrhea, chronic pelvic pain and infertility. Luoshi Neiyi Prescription …