Bacteriophages of the human gut: the “known unknown” of the microbiome

AN Shkoporov, C Hill - Cell host & microbe, 2019 - cell.com
The human gut microbiome is a dense and taxonomically diverse consortium of
microorganisms. While the bacterial components of the microbiome have received …

Antibiotic use and microbiome function

M Ferrer, C Méndez-García, D Rojo, C Barbas… - Biochemical …, 2017 - Elsevier
Our microbiome should be understood as one of the most complex components of the
human body. The use of β-lactam antibiotics is one of the microbiome covariates that …

The human intestinal virome in health and disease

SR Carding, N Davis, L Hoyles - Alimentary pharmacology & …, 2017 - Wiley Online Library
Background The human virome consists of animal‐cell viruses causing transient infections,
bacteriophage (phage) predators of bacteria and archaea, endogenous retroviruses and …

Phages and their potential to modulate the microbiome and immunity

S Federici, SP Nobs, E Elinav - Cellular & molecular immunology, 2021 - nature.com
Bacteriophages (hence termed phages) are viruses that target bacteria and have long been
considered as potential future treatments against antibiotic-resistant bacterial infection …

Exploring the human microbiome from multiple perspectives: factors altering its composition and function

D Rojo, C Méndez-García… - FEMS microbiology …, 2017 - academic.oup.com
Our microbiota presents peculiarities and characteristics that may be altered by multiple
factors. The degree and consequences of these alterations depend on the nature, strength …

Defining the human gut host–phage network through single-cell viral tagging

M Džunková, SJ Low, JN Daly, L Deng, C Rinke… - Nature …, 2019 - nature.com
Viral discovery is accelerating at an unprecedented rate due to continuing advances in
culture-independent sequence-based analyses. One important facet of this discovery is …

Challenges of studying the human virome–relevant emerging technologies

MK Mirzaei, J Xue, R Costa, J Ru, S Schulz… - Trends in …, 2021 - cell.com
In this review we provide an overview of current challenges and advances in bacteriophage
research within the growing field of viromics. In particular, we discuss, from a human virome …

[HTML][HTML] Emerging technologies in the study of the virome

SE Smith, W Huang, K Tiamani, M Unterer… - Current opinion in …, 2022 - Elsevier
Highlights•New amplification methods reduce biases caused by whole genome
amplification•Biases caused by assembly can be avoided using long-read …

[HTML][HTML] A plate of viruses: Viral metagenomics of supermarket chicken, pork and beef from Brazil

S Cibulski, DA de Lima, HF Dos Santos, TF Teixeira… - Virology, 2021 - Elsevier
A viral metagenomics study was conducted in beef, pork, and chicken sold in supermarkets
from Southern Brazil. From chicken, six distinct gyroviruses (GyV) were detected, including …

De novo sequence assembly requires bioinformatic checking of chimeric sequences

LS Arroyo Mühr, C Lagheden, SS Hassan, SN Kleppe… - Plos one, 2020 - journals.plos.org
De novo assembly of sequence reads from next generation sequencing platforms is a
common strategy for detecting presence and sequencing of viruses in biospecimens …