MirDIP is a well-established database that aggregates microRNA-gene human interactions
from multiple databases to increase coverage, reduce bias, and improve usability by …

MicroRNAs (miRNAs) have emerged as a prominent layer of regulation of gene expression.
This article offers the salient and current aspects of machine learning (ML) tools and …

Background: Small, non-coding microRNAs, usually of 20-25 nucleotides, are known to
regulate the post-transcriptional gene expression, which has a significant role in human …

Background/Aims: Previous studies have suggested that autophagy is activated in distinct
cerebrovascular diseases, including stroke. However, the underlying regulatory mechanism …

Identification of miRNA–mRNA interactions is critical to understand the new paradigms in
gene regulation. Existing methods show suboptimal performance owing to inappropriate …

Cytochromes P450 (CYP) are enzymes responsible for the biotransformation of most
endogenous and exogenous agents. The expression of each CYP is influenced by a unique …

Current bioinformatics databases provide huge amounts of different biological entities such
as genes, proteins, diseases, microRNA, annotations, literature references. In many case …

The Ascidian C. robusta is a powerful model for studying innate immunity. LPS induction
activates inflammatory-like reactions in the pharynx and the expression of several innate …

The transforming growth factor-β (TGF-β) family of cytokines performs a multifunctional
signaling, which is integrated and coordinated in a signaling network that involves other …

Background Ovarian cancer (OC) is a gynecological malignancy with the highest mortality
rate. Cisplatin (DDP) based chemotherapy is a standard strategy for ovarian cancer. Despite …