Heavy metals and human health: Possible exposure pathways and the competition for protein binding sites
D Witkowska, J Słowik, K Chilicka - Molecules, 2021 - mdpi.com
Heavy metals enter the human body through the gastrointestinal tract, skin, or via inhalation.
Toxic metals have proven to be a major threat to human health, mostly because of their …
Toxic metals have proven to be a major threat to human health, mostly because of their …
Metallothionein diversity and distribution in the tree of life: a multifunctional protein
A Ziller, L Fraissinet-Tachet - Metallomics, 2018 - academic.oup.com
MTs are small cysteine-rich proteins that chelate metal ions such as Cu+ and Zn2+, and are
widely distributed in several life domains, in particular the eukaryotic one. They are present …
widely distributed in several life domains, in particular the eukaryotic one. They are present …
Pollutant toxicology with respect to microalgae and cyanobacteria
Microalgae and cyanobacteria are fundamental components of aquatic ecosystems.
Pollution in aquatic environment is a worldwide problem. Toxicological research on …
Pollution in aquatic environment is a worldwide problem. Toxicological research on …
Genomic and non-genomic mechanisms of action of thyroid hormones and their catabolite 3, 5-diiodo-l-thyronine in mammals
M Giammanco, CM Di Liegro, G Schiera… - International Journal of …, 2020 - mdpi.com
Since the realization that the cellular homologs of a gene found in the retrovirus that
contributes to erythroblastosis in birds (v-erbA), ie the proto-oncogene c-erbA encodes the …
contributes to erythroblastosis in birds (v-erbA), ie the proto-oncogene c-erbA encodes the …
Identifying and characterizing stress pathways of concern for consumer safety in next-generation risk assessment
S Hatherell, MT Baltazar, J Reynolds… - Toxicological …, 2020 - academic.oup.com
Many substances for which consumer safety risk assessments need to be conducted are not
associated with specific toxicity modes of action, but rather exhibit nonspecific toxicity …
associated with specific toxicity modes of action, but rather exhibit nonspecific toxicity …
[HTML][HTML] Nano-selenium alleviates cadmium-induced cerebellar injury by activating metal regulatory transcription factor 1 mediated metal response
SS Bi, M Talukder, HT Jin, MW Lv, J Ge, C Zhang, JL Li - Animal Nutrition, 2022 - Elsevier
This study aims to investigate the role of metal regulatory transcription factor 1 (MTF1)-
mediated metal response in cadmium (Cd)-induced cerebellar injury, and to evaluate the …
mediated metal response in cadmium (Cd)-induced cerebellar injury, and to evaluate the …
[HTML][HTML] Transcriptomic and proteomic responses of silver nanoparticles in hepatocyte-like cells derived from human induced pluripotent stem cells
X Gao, R Li, JJ Yourick, RL Sprando - Toxicology in Vitro, 2022 - Elsevier
Silver nanoparticles (AgNPs) have been increasingly used in a variety of consumer products
over the last decades. However, their potential adverse effects have not been fully …
over the last decades. However, their potential adverse effects have not been fully …
Cadmium through disturbing MTF1-mediated metal response induced cerebellar injury
SS Bi, M Talukder, HT Jin, MW Lv, J Ge, C Zhang… - Neurotoxicity …, 2022 - Springer
Cadmium (Cd) is a toxic environmental contaminant, which bio-accumulate in animals
through the food chain. Cerebellum is one of the primary target organs for Cd exposure. In …
through the food chain. Cerebellum is one of the primary target organs for Cd exposure. In …
Non-enzymatic antioxidant responses of Mytilus galloprovincialis: Insights into the physiological role against metal-induced oxidative stress
G Santovito, E Trentin, I Gobbi, P Bisaccia… - … and Physiology Part C …, 2021 - Elsevier
The exposure to metals is known to generate oxidative stress in living organisms, which can
result in the induction of protective antioxidant defences, both enzymatic and non-enzymatic …
result in the induction of protective antioxidant defences, both enzymatic and non-enzymatic …
Thymoquinone induces Nrf2 mediated adaptive homeostasis: Implication for mercuric chloride-induced nephrotoxicity
Background: the primary function of the kidney is to eliminate metabolic waste products and
xenobiotics from the circulation. During this process, the kidney may become vulnerable to …
xenobiotics from the circulation. During this process, the kidney may become vulnerable to …