Liver fibrosis–from bench to bedside

SL Friedman - Journal of hepatology, 2003 - Elsevier
Liver fibrosis has evolved in the past 20 years from a pure laboratory discipline to an area of
great bedside relevance to practicing hepatologists. This evolution reflects growing awarenessnotonlyofthemolecularunderpinn …

American Gastroenterological Association technical review on the management of hepatitis C

JL Dienstag, JG McHutchison - Revista de Gastroenterología de …, 2006 - medigraphic.com
Abreviaturas usadas en este Trabajo: IC: intervalo de confianza; RVT: respuesta virológica
temprana; TAAA: terapia antirretroviral altamente activa; IHA: índice histiológico activo; VIH …

Sampling variability of liver fibrosis in chronic hepatitis C

P Bedossa, D Dargère, V Paradis - Hepatology, 2003 - journals.lww.com
Fibrosis is a common endpoint of clinical trials in chronic hepatitis C, and liver biopsy
remains the gold standard for fibrosis evaluation. However, variability in the distribution of …

Magnetic resonance elastography for the noninvasive staging of liver fibrosis

L Huwart, C Sempoux, E Vicaut, N Salameh, L Annet… - Gastroenterology, 2008 - Elsevier
Background & Aims: The purpose of our study was to prospectively compare the success
rate and diagnostic accuracy of magnetic resonance elastography, ultrasound elastography …

A systematic review of the quality of liver biopsy specimens

E Cholongitas, M Senzolo, R Standish… - American journal of …, 2006 - academic.oup.com
Characteristics for an optimal liver biopsy specimen were recently defined as 20 to 25 mm
long and/or containing more than 11 complete portal tracts (CPTs). A systematic review of …

Progression of hepatic fibrosis in patients with hepatitis C: a prospective repeat liver biopsy study

SD Ryder - Gut, 2004 - gut.bmj.com
Background: The natural history of hepatitis C virus (HCV) infection remains uncertain.
Previous data concerning rates of progression are from studies using estimated dates of …

[PDF][PDF] Prognostic value of Ishak fibrosis stage: findings from the hepatitis C antiviral long‐term treatment against cirrhosis trial

JE Everhart, EC Wright, ZD Goodman, JL Dienstag… - …, 2010 - Wiley Online Library
Studies of the prognostic value of Ishak fibrosis stage are lacking. We used multi‐year follow‐
up of the Hepatitis C Antiviral Long‐Term Treatment Against Cirrhosis (HALT‐C) Trial to …

Influence of alcohol on the progression of hepatitis C virus infection: a meta-analysis

SJ Hutchinson, SM Bird, DJ Goldberg - Clinical Gastroenterology and …, 2005 - Elsevier
Background & Aims: A convincing, yet inconsistent, pattern has emerged that demonstrates
increased progression of HCV-related liver disease with heavy alcohol use. The aim was to …

[PDF][PDF] Intrahepatic levels of CXCR3‐associated chemokines correlate with liver inflammation and fibrosis in chronic hepatitis C

M Zeremski, LM Petrovic, L Chiriboga, QB Brown… - …, 2008 - Wiley Online Library
Chemokines, chemotactic cytokines, may promote hepatic inflammation in chronic hepatitis
C virus (HCV) infection through the recruitment of lymphocytes to the liver parenchyma. We …

Steatosis accelerates fibrosis development over time in hepatitis C virus genotype 3 infected patients

J Westin, H Nordlinder, M Lagging, G Norkrans… - Journal of …, 2002 - Elsevier
Background/Aims: Steatosis is common in patients with hepatitis C virus (HCV) infection. Its
influence on disease progression is only partially understood. The aim of this study was to …