Bacterial type III secretion systems: a complex device for the delivery of bacterial effector proteins into eukaryotic host cells
Virulence-associated type III secretion systems (T3SS) serve the injection of bacterial
effector proteins into eukaryotic host cells. They are able to secrete a great diversity of …
effector proteins into eukaryotic host cells. They are able to secrete a great diversity of …
Type III secretion: building and operating a remarkable nanomachine
AG Portaliou, KC Tsolis, MS Loos, V Zorzini… - Trends in biochemical …, 2016 - cell.com
The Type III secretion system (T3SS) is a protein export pathway that is widespread in Gram-
negative bacteria and delivers effector proteins directly into eukaryotic cells. At its core lie …
negative bacteria and delivers effector proteins directly into eukaryotic cells. At its core lie …
Visualization of the type III secretion mediated Salmonella–host cell interface using cryo-electron tomography
Many important gram-negative bacterial pathogens use highly sophisticated type III protein
secretion systems (T3SSs) to establish complex host-pathogen interactions. Bacterial-host …
secretion systems (T3SSs) to establish complex host-pathogen interactions. Bacterial-host …
The structure and function of type III secretion systems
RQ Notti, CE Stebbins - Virulence mechanisms of bacterial …, 2016 - Wiley Online Library
Type III secretion systems (T3SSs) afford Gram‐negative bacteria an intimate means of
altering the biology of their eukaryotic hosts—the direct delivery of effector proteins from the …
altering the biology of their eukaryotic hosts—the direct delivery of effector proteins from the …
Salmonella Interacts With Autophagy to Offense or Defense
S Wu, Y Shen, S Zhang, Y Xiao, S Shi - Frontiers in Microbiology, 2020 - frontiersin.org
Autophagy is an important component of the innate immune system in mammals. Low levels
of basic autophagy are sustained in normal cells, to help with the clearance of aging …
of basic autophagy are sustained in normal cells, to help with the clearance of aging …
The type III secretion system needle, tip, and translocon
Many Gram‐negative bacteria pathogenic to plants and animals deploy the type III secretion
system (T3SS) to inject virulence factors into their hosts. All bacteria that rely on the T3SS to …
system (T3SS) to inject virulence factors into their hosts. All bacteria that rely on the T3SS to …
Type three secretion system in Salmonella Typhimurium: the key to infection
AMP Dos Santos, RG Ferrari, CA Conte-Junior - Genes & genomics, 2020 - Springer
Abstract Background Type Three Secretion Systems (T3SS) are nanomachine complexes,
which display the ability to inject effector proteins directly into host cells. This skill allows for …
which display the ability to inject effector proteins directly into host cells. This skill allows for …
Virulence-associated type III secretion systems in Gram-negative bacteria
Virulence-associated bacterial type III secretion systems are multiprotein molecular
machines that promote the pathogenicity of bacteria towards eukaryotic host cells. These …
machines that promote the pathogenicity of bacteria towards eukaryotic host cells. These …
Type 3 secretion system 1 of Salmonella typhimurium and its inhibitors: a novel strategy to combat salmonellosis
S Hussain, P Ouyang, Y Zhu, A Khalique, C He… - … Science and Pollution …, 2021 - Springer
Unsuccessful vaccination against Salmonella due to a large number of serovars, and
antibiotic resistance, necessitates the development of novel therapeutics to treat …
antibiotic resistance, necessitates the development of novel therapeutics to treat …
Three‐dimensional electron microscopy reconstruction and cysteine‐mediated crosslinking provide a model of the type III secretion system needle tip complex
Type III secretion systems are found in many G ram‐negative bacteria. They are activated by
contact with eukaryotic cells and inject virulence proteins inside them. Host cell detection …
contact with eukaryotic cells and inject virulence proteins inside them. Host cell detection …