Drug-induced lupus erythematosus: an update on drugs and mechanisms
Y He, AH Sawalha - Current opinion in rheumatology, 2018 - journals.lww.com
The list of drugs implicated in triggering DILE is expanding as new drugs with novel
mechanisms of action are being developed. It is important to recognize culprit drugs that …
mechanisms of action are being developed. It is important to recognize culprit drugs that …
[PDF][PDF] Comprehensive Management of Hypertension: Strategies, Guidelines, and Emerging Therapies
I Karunarathna, K Kusumarathna… - Uva Clinical Lab …, 2024 - researchgate.net
Hypertension, a leading risk factor for cardiovascular disease, poses a significant public
health challenge globally. This article explores the multifaceted approach to hypertension …
health challenge globally. This article explores the multifaceted approach to hypertension …
[HTML][HTML] Antihypertensive medications
H Khalil, R Zeltser - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Antihypertensive Medications - StatPearls - NCBI Bookshelf US flag An official website of the
United States government Here's how you know NIH NLM Logo Access keys NCBI Homepage …
United States government Here's how you know NIH NLM Logo Access keys NCBI Homepage …
Effect of N‐Acetyltransferase 2 Genotype on the Pharmacokinetics of Hydralazine During Pregnancy
LW Han, RJ Ryu, M Cusumano… - The Journal of …, 2019 - Wiley Online Library
Hydralazine, an antihypertensive agent used during pregnancy, undergoes N‐acetylation
primarily via N‐acetyltransferase 2 (NAT2) to form 3‐methyl‐1, 2, 4‐triazolo [3, 4‐a] …
primarily via N‐acetyltransferase 2 (NAT2) to form 3‐methyl‐1, 2, 4‐triazolo [3, 4‐a] …
[HTML][HTML] Hydralazine
LL Herman, ZS Bruss, VS Tivakaran - 2017 - europepmc.org
Objectives: Identify the indications for initiating hydralazine therapy. Summarize the
theorized mechanism of action of hydralazine. Discuss the parameters of hydralazine …
theorized mechanism of action of hydralazine. Discuss the parameters of hydralazine …
ANA‐Negative Hydralazine‐Induced Pericardial Effusion
V Zeitjian, A Mehdizadeh - Case Reports in Medicine, 2017 - Wiley Online Library
This case describes a patient with pericardial effusion as a phenomenon of the drug‐
induced lupus erythematosus (DILE) syndrome due to hydralazine. The relevance of this …
induced lupus erythematosus (DILE) syndrome due to hydralazine. The relevance of this …
[HTML][HTML] A suspected case of hydralazine-induced hepatotoxicity: a case report and review of literature
M Sharma, M Foge, D Mascarenhas - The American journal of case …, 2018 - ncbi.nlm.nih.gov
Objective: Rare disease Background: Hydralazine is an effective antihypertensive agent but
may rarely have devastating hepatotoxic effects that are extremely variable, thus making the …
may rarely have devastating hepatotoxic effects that are extremely variable, thus making the …
An Insight-Based Computational Approaches to Estimate Molecular Weight Distribution, Allergenicity and Immunological Aspects, Toxicity Profile, Possible …
MS Bensaad, MA Kahoul, M Khier… - Journal of Biobased …, 2023 - ingentaconnect.com
Clinical pharmacology and toxicology are considered nowadays two complementary and
indispensable medical disciplines that allowed clinicians to achieve the optimal therapeutic …
indispensable medical disciplines that allowed clinicians to achieve the optimal therapeutic …
[HTML][HTML] Antinuclear antibody-negative lupus? An ominous presentation of hydralazine-induced lupus syndrome
T Solomon-Tsegaye, EL Treadwell, R Obi… - European journal of …, 2018 - ncbi.nlm.nih.gov
Up to 10% of systemic lupus erythematosus (SLE) cases are drug-induced; hence, they are
called drug-induced lupus syndrome (DILS). Antinuclear antibody (ANA) should be present …
called drug-induced lupus syndrome (DILS). Antinuclear antibody (ANA) should be present …
[HTML][HTML] A case of seronegative ANA hydralazine-induced lupus presenting with pericardial effusion and pleural effusion
KO Elkholy, H Akhtar, A Chakraborti - Cureus, 2020 - ncbi.nlm.nih.gov
Hydralazine induced lupus syndrome (HILS), a form of Drug-Induced Lupus (DIL), was first
reported in 1953. Since then, studies have shown an increasing incidence of HILS. It …
reported in 1953. Since then, studies have shown an increasing incidence of HILS. It …