Formulation of nanospanlastics as a promising approach for‎ improving the topical delivery of a natural leukotriene inhibitor (3-‎ acetyl-11-keto-β-boswellic acid) …

F Badria, E Mazyed - Drug design, development and therapy, 2020 - Taylor & Francis
Purpose The current study aimed to discuss the potential of nanospanlastics as a surfactant-
based vesicular system for improving the topical delivery of 3-acetyl-11-keto-β-boswellic …

Formulation and optimization of nanospanlastics for improving the bioavailability of green tea epigallocatechin gallate

EA Mazyed, DA Helal, MM Elkhoudary… - Pharmaceuticals, 2021 - mdpi.com
The present study aimed to investigate the potential of nanospanlastics for boosting the
bioavailability of epigallocatechin gallate (EGCG). EGCG has valuable effects like anti …

Development of provesicular nanodelivery system of curcumin as a safe and effective antiviral agent: statistical optimization, in vitro characterization, and antiviral …

FA Badria, AE Abdelaziz, AH Hassan, AA Elgazar… - Molecules, 2020 - mdpi.com
Curcumin is a natural compound that has many medical applications. However, its low
solubility and poor stability could impede its clinical applications. The present study aimed to …

Preparation, characterization, and ex-vivo evaluation of curcumin-loaded niosomal nanoparticles on the equine sperm quality during cooled storage

N Nasiri-Foomani, M Ebadi, S Hassani… - International Journal of …, 2024 - Elsevier
Oxidative damage to sperm during cooled storage is a significant issue, and curcumin, with
its antioxidant properties, could be a solution. However, its low bioavailability presents a …

Fabrication of transgelosomes for enhancing the ocular delivery of acetazolamide: Statistical optimization, in vitro characterization, and in vivo study

EA Mazyed, AE Abdelaziz - Pharmaceutics, 2020 - mdpi.com
Acetazolamide (ACZ) is a potent carbonic anhydrase inhibitor that is used for the treatment
of glaucoma. Its oral administration causes various undesirable side effects. This study …

Development of cyclodextrin-functionalized transethoniosomes of 6-gingerol: statistical optimization, in vitro characterization and assessment of cytotoxic and anti …

EA Mazyed, FA Badria, MH ElNaggar, SM El-Masry… - Pharmaceutics, 2022 - mdpi.com
The poor solubility and stability of 6-gingerol (6-G) could hamper its clinical applications.
The aim of the current study was to develop a novel ultra-deformable cyclodextrin …

Formulation of sodium valproate nanospanlastics as a promising approach for drug repurposing in the treatment of androgenic alopecia

FA Badria, HA Fayed, AK Ibraheem, AF State… - Pharmaceutics, 2020 - mdpi.com
Sodium valproate (SV) is an antiepileptic drug that is widely used in the treatment of different
seizure disorders. The topical SV has a hair regenerative potential through activating the …

[HTML][HTML] Formulation, optimization and evaluation of ocular gel containing nebivolol Hcl-loaded ultradeformable spanlastics nanovesicles: in vitro and in vivo studies

M Yasser, EE El Naggar, N Elfar, MH Teaima… - International Journal of …, 2024 - Elsevier
The study aims to improve the ocular delivery of Nebivolol HCL (NBV) belonging to the
Biopharmaceutics classification system (BCSII) by using spanlastic nanovesicles (SNVs) for …

[HTML][HTML] Formulation of Glibenclamide proniosomes for oral administration: Pharmaceutical and pharmacodynamics evaluation

D Alshora, M Ibrahim, N Alanazi, M Alowyid… - Saudi Pharmaceutical …, 2023 - Elsevier
Glibenclamide (GB), oral antidiabetic sulfonylurea, is used in the management of diabetes
mellitus type II. It suffers from low bioavailability due to low water solubility. This work aimed …

Appraisal terpenoids rich Boswellia carterri ethyl acetate extract in binary cyclodextrin oligomer nano complex for improving respiratory distress

BMM Ibrahim, AB Darwish, SA Taleb, RM Mourad… - Scientific Reports, 2024 - nature.com
Boswellia carterii (BC) resins plants have a long historical background as a treatment for
inflammation, as indicated by information originating from multiple countries. Twenty-seven …