The progress in understanding and treatment of diabetic retinopathy

AW Stitt, TM Curtis, M Chen, RJ Medina… - Progress in retinal and …, 2016 - Elsevier
Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and
remains a leading cause of vision loss globally. Its aetiology and pathology have been …

[HTML][HTML] The pathology associated with diabetic retinopathy

J Lechner, OE O'Leary, AW Stitt - Vision research, 2017 - Elsevier
This review summarizes the pathological features of diabetic retinopathy. The lesions
occurring in the diabetic retina have been described over many decades using descriptive …

[HTML][HTML] Predicting the risk of developing diabetic retinopathy using deep learning

A Bora, S Balasubramanian, B Babenko… - The Lancet Digital …, 2021 - thelancet.com
Background Diabetic retinopathy screening is instrumental to preventing blindness, but
scaling up screening is challenging because of the increasing number of patients with all …

Photoreceptor cells and RPE contribute to the development of diabetic retinopathy

D Tonade, TS Kern - Progress in retinal and eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …

Diabetic retinopathy: hyperglycaemia, oxidative stress and beyond

HP Hammes - Diabetologia, 2018 - Springer
Diabetic retinopathy remains a relevant clinical problem. In parallel with diagnostic and
therapeutic improvements, the role of glycaemia and reactive metabolites causing cell stress …

Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives

R Simo, C Hernández - Trends in Endocrinology & Metabolism, 2014 - cell.com
Diabetic retinopathy (DR), one of the leading causes of preventable blindness, has been
considered a microcirculatory disease of the retina. However, there is emerging evidence to …

Early detection of diabetic retinopathy

H Safi, S Safi, A Hafezi-Moghadam… - Survey of ophthalmology, 2018 - Elsevier
Diabetic retinopathy (DR) is a primary cause of visual impairment worldwide. Diabetes
mellitus may be associated with ophthalmoscopically nonvisible neurovascular damage that …

Retina in a dish: Cell cultures, retinal explants and animal models for common diseases of the retina

S Schnichels, F Paquet-Durand, M Löscher… - Progress in retinal and …, 2021 - Elsevier
For many retinal diseases, including age-related macular degeneration (AMD), glaucoma,
and diabetic retinopathy (DR), the exact pathogenesis is still unclear. Moreover, the currently …

Pathophysiology of diabetic retinopathy: the old and the new

S Kusuhara, Y Fukushima, S Ogura… - Diabetes & …, 2018 - synapse.koreamed.org
Vision loss in diabetic retinopathy (DR) is ascribed primarily to retinal vascular abnormalities—
including hyperpermeability, hypoperfusion, and neoangiogenesis—that eventually lead to …

Decreased retinal ganglion cell layer thickness in patients with type 1 diabetes

HW Van Dijk, FD Verbraak, PHB Kok… - … & visual science, 2010 - iovs.arvojournals.org
Purpose.: To determine which retinal layers are most affected by diabetes and contribute to
thinning of the inner retina and to investigate the relationship between retinal layer thickness …