The tectum/superior colliculus as the vertebrate solution for spatial sensory integration and action

T Isa, E Marquez-Legorreta, S Grillner, EK Scott - Current Biology, 2021 - cell.com
The superior colliculus, or tectum in the case of non-mammalian vertebrates, is a part of the
brain that registers events in the surrounding space, often through vision and hearing, but …

Unraveling circuits of visual perception and cognition through the superior colliculus

MA Basso, ME Bickford, J Cang - Neuron, 2021 - cell.com
The superior colliculus is a conserved sensorimotor structure that integrates visual and other
sensory information to drive reflexive behaviors. Although the evidence for this is strong and …

A dual-channel optogenetic stimulator selectively modulates distinct defensive behaviors

X Cai, L Li, W Liu, N Du, Y Zhao, Y Han, C Liu, Y Yin… - Iscience, 2022 - cell.com
Implantable devices and systems have been emerging as powerful tools for neuroscience
research and medical applications. Here we report a wireless, dual-channel optoelectronic …

Neural circuit mechanisms involved in animals' detection of and response to visual threats

Q Wu, Y Zhang - Neuroscience Bulletin, 2023 - Springer
Evading or escaping from predators is one of the most crucial issues for survival across the
animal kingdom. The timely detection of predators and the initiation of appropriate fight-or …

Anatomical and electrophysiological analysis of cholinergic inputs from the parabigeminal nucleus to the superficial superior colliculus

K Tokuoka, M Kasai, K Kobayashi… - Journal of …, 2020 - journals.physiology.org
Superior colliculus (SC) is a midbrain structure that integrates sensory inputs and generates
motor commands to initiate innate motor behaviors. Its retinorecipient superficial layers …

An integrative role for the superior colliculus in selecting targets for movements

AB Wolf, MJ Lintz, JD Costabile… - Journal of …, 2015 - journals.physiology.org
A fundamental goal of systems neuroscience is to understand the neural mechanisms
underlying decision making. The midbrain superior colliculus (SC) is known to be central to …

Whisker-related afferents in superior colliculus

MA Castro-Alamancos… - Journal of …, 2016 - journals.physiology.org
Rodents use their whiskers to explore the environment, and the superior colliculus is part of
the neural circuits that process this sensorimotor information. Cells in the intermediate layers …

Optogenetic surface stimulation of the rat cervical spinal cord

SE Mondello, MD Sunshine… - Journal of …, 2018 - journals.physiology.org
Electrical intraspinal microstimulation (ISMS) at various sites along the cervical spinal cord
permits forelimb muscle activation, elicits complex limb movements and may enhance …

Behavioral status influences the dependence of odorant-induced change in firing on prestimulus firing rate

A Li, EM Guthman, WT Doucette… - Journal of …, 2017 - Soc Neuroscience
The firing rate of the mitral/tufted cells in the olfactory bulb is known to undergo significant
trial-to-trial variability and is affected by anesthesia. Here we ask whether odorant-elicited …

The basal forebrain modulates neuronal response in an active olfactory discrimination task

A Nunez-Parra, CA Cea-Del Rio… - Frontiers in cellular …, 2020 - frontiersin.org
Successful completion of sensory decision-making requires focusing on relevant stimuli,
adequate signal/noise ratio for stimulus discrimination, and stimulus valence evaluation …