Medicinal chemistry approaches for the discovery of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors as antimalarial agents
Malaria is a severe human disease and a global health problem because of drug-resistant
strains. Drugs reported to prevent the growth of Plasmodium parasites target various phases …
strains. Drugs reported to prevent the growth of Plasmodium parasites target various phases …
Menthol: An underestimated anticancer agent
Y Zhao, H Pan, W Liu, E Liu, Y Pang, H Gao… - Frontiers in …, 2023 - frontiersin.org
Menthol, a widely used natural, active compound, has recently been shown to have
anticancer activity. Moreover, it has been found to have a promising future in the treatment of …
anticancer activity. Moreover, it has been found to have a promising future in the treatment of …
Preformulation Studies of Novel Menthol Prodrugs with Antiparasitic Activity: Chemical Stability, In Silico, and In Vitro Permeability Assays
CM Clemente, R Onnainty, N Usseglio… - Drugs and Drug …, 2023 - mdpi.com
Based on the demonstrated and reported trypanocidal, leishmanicidal, and antiplasmodial
activities of two menthol prodrugs, it was decided to proceed with preformulation studies …
activities of two menthol prodrugs, it was decided to proceed with preformulation studies …