Clonal hematopoiesis of indeterminate potential predicts adverse outcomes in patients with atherosclerotic cardiovascular disease
Background Clonal hematopoiesis of indeterminate potential (CHIP)—the age-related clonal
expansion of blood stem cells with leukemia-associated mutations—is a novel …
expansion of blood stem cells with leukemia-associated mutations—is a novel …
Germline Predisposition for Clonal Hematopoiesis
Clonal hematopoiesis (CH) is an entity hallmarked by skewed hematopoiesis with persistent
overrepresentation of cells from a common stem/progenitor lineage harboring single …
overrepresentation of cells from a common stem/progenitor lineage harboring single …
Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias
Abstract Background and Aims Clonal haematopoiesis of indeterminate potential (CHIP), the
age-related expansion of blood cells with preleukemic mutations, is associated with …
age-related expansion of blood cells with preleukemic mutations, is associated with …
Birth weight is associated with clonal hematopoiesis of indeterminate potential and cardiovascular outcomes in adulthood
Background High and low birth weight are independently associated with increased
cardiovascular disease risk in adulthood. Clonal hematopoiesis of indeterminate potential …
cardiovascular disease risk in adulthood. Clonal hematopoiesis of indeterminate potential …
[HTML][HTML] Long-term longitudinal analysis of 4,187 participants reveals new insights into determinants of incident clonal hematopoiesis
MM Uddin, S Saadatagah, A Niroula, B Yu, W Hornsby… - medRxiv, 2023 - ncbi.nlm.nih.gov
Clonal hematopoiesis (CH), characterized by blood cells predominantly originating from a
single mutated hematopoietic stem cell, is linked to diverse aging-related diseases …
single mutated hematopoietic stem cell, is linked to diverse aging-related diseases …
Multi-ancestry genome-wide association meta-analysis of mosaic loss of chromosome Y in the Million Veteran Program identifies 167 novel loci
Mosaic loss of chromosome Y (mLOY) is a common somatic mutation in leukocytes of older
males. mLOY was detected in 126,108 participants of the Million Veteran Program: 106,054 …
males. mLOY was detected in 126,108 participants of the Million Veteran Program: 106,054 …