The role of proprotein convertases in the regulation of the function of immune cells in the oncoimmune response
Proprotein convertases (PC) are a family of 9 serine proteases involved in the processing of
cellular pro-proteins. They trigger the activation, inactivation or functional changes of many …
cellular pro-proteins. They trigger the activation, inactivation or functional changes of many …
Ablation of PC1/3 in POMC-Expressing Tissues but Not in Immune Cells Induces Sepsis Hypersensitivity
J Moeller, DT Meier - Journal of the Endocrine Society, 2024 - academic.oup.com
Abstract Prohormone convertase 1/3 (PC1/3) is an endopeptidase required for the
processing of neuropeptide and endocrine peptide precursors; it is expressed in …
processing of neuropeptide and endocrine peptide precursors; it is expressed in …
PC1/3 KD macrophages exhibit resistance to the inhibitory effect of IL-10 and a higher TLR4 activation rate, leading to an anti-tumoral phenotype
F Rodet, A Capuz, BA Ozcan, R Le Beillan… - Cells, 2019 - mdpi.com
During tumorigenesis, macrophages are recruited by tumors and orientated towards a pro-
tumoral phenotype. One of the main anti-tumoral immunotherapy consists of their re …
tumoral phenotype. One of the main anti-tumoral immunotherapy consists of their re …
Epigenetic Studies Revealed a Ghost Proteome in PC1/3 KD Macrophages under Antitumoral Resistance Induced by IL-10
Our previous investigation on macrophages has allowed us to show that the inhibition of the
enzyme proprotein convertase (PC1/3) controls the activation of macrophages. We …
enzyme proprotein convertase (PC1/3) controls the activation of macrophages. We …
Semysinthetic biflavonoid Morelloflavone-7, 4′, 7 ″, 3‴, 4‴-penta-O-butanoyl is a more potent inhibitor of Proprotein Convertases Subtilisin/Kexin PC1/3 than Kex2 …
AA de Souza, DM de Andrade… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Background Garcinia brasiliensis is a species native to the Amazon forest. The white
mucilaginous pulp is used in folk medicine as a wound healing agent and for peptic ulcer …
mucilaginous pulp is used in folk medicine as a wound healing agent and for peptic ulcer …
La Proprotéine convertase 1/3, enzyme clé du système neuroendocrinien, est un régulateur majeur de la réponse immunitaire: Un modèle de plasticité fonctionnelle
F Rodet - 2022 - lilloa.univ-lille.fr
Alors que des cellules comme les cellules immunitaires étaient auparavant considérées
comme différenciées de façon irrévocable, celles-ci peuvent en réalité présenter une …
comme différenciées de façon irrévocable, celles-ci peuvent en réalité présenter une …
[引用][C] Biotechnology in Europe: A challenge for Central and East European countries.
Biotechnology in Europe: A challenge for Central and East European countries. - Abstract -
Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About Tools …
Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About Tools …