Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility
CB Klune, B Jin, LA DeNardo - Elife, 2021 - elifesciences.org
The medial prefrontal cortex (mPFC) and its abundant connections with other brain regions
play key roles in memory, cognition, decision making, social behaviors, and mood …
play key roles in memory, cognition, decision making, social behaviors, and mood …
Opportunities and limitations of genetically modified nonhuman primate models for neuroscience research
The recently developed new genome-editing technologies, such as the CRISPR/Cas
system, have opened the door for generating genetically modified nonhuman primate (NHP) …
system, have opened the door for generating genetically modified nonhuman primate (NHP) …
Diversity of interneurons in the dorsal striatum revealed by single-cell RNA sequencing and PatchSeq
Striatal locally projecting neurons, or interneurons, act on nearby circuits and shape
functional output to the rest of the basal ganglia. We performed single-cell RNA sequencing …
functional output to the rest of the basal ganglia. We performed single-cell RNA sequencing …
[HTML][HTML] Joint hypermobility links neurodivergence to dysautonomia and pain
JLL Csecs, V Iodice, CL Rae, A Brooke… - Frontiers in …, 2022 - frontiersin.org
Objectives Autism, attention deficit hyperactivity disorder (ADHD), and tic disorder (Tourette
syndrome; TS) are neurodevelopmental conditions that frequently co-occur and impact …
syndrome; TS) are neurodevelopmental conditions that frequently co-occur and impact …
Antibodies from children with PANDAS bind specifically to striatal cholinergic interneurons and alter their activity
J Xu, RJ Liu, S Fahey, L Frick… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: Pediatric obsessive-compulsive disorder (OCD) sometimes appears rapidly, even
overnight, often after an infection. Pediatric autoimmune neuropsychiatric disorders …
overnight, often after an infection. Pediatric autoimmune neuropsychiatric disorders …
[图书][B] Communication issues in autism and Asperger syndrome: Do we speak the same language?
O Bogdashina - 2022 - books.google.com
In this updated edition, Olga Bogdashina provides a theoretical foundation for
understanding communication and language impairments specific to autism. She explores …
understanding communication and language impairments specific to autism. She explores …
Evolutionarily conservative and non-conservative regulatory networks during primate interneuron development revealed by single-cell RNA and ATAC sequencing
The differences in size and function between primate and rodent brains, and the association
of disturbed excitatory/inhibitory balance with many neurodevelopmental disorders highlight …
of disturbed excitatory/inhibitory balance with many neurodevelopmental disorders highlight …
Dopaminergic disturbances in Tourette syndrome: an integrative account
TV Maia, VA Conceição - Biological psychiatry, 2018 - Elsevier
Tourette syndrome (TS) is thought to involve dopaminergic disturbances, but the nature of
those disturbances remains controversial. Existing hypotheses suggest that TS involves 1) …
those disturbances remains controversial. Existing hypotheses suggest that TS involves 1) …
NMDA receptor hypofunction underlies deficits in parvalbumin interneurons and social behavior in neuroligin 3 R451C knockin mice
Neuroligins (NLs), a family of postsynaptic cell-adhesion molecules, have been associated
with autism spectrum disorder. We have reported that dysfunction of the medial prefrontal …
with autism spectrum disorder. We have reported that dysfunction of the medial prefrontal …
Human pluripotent stem cell (hPSC) and organoid models of autism: opportunities and limitations
S Kilpatrick, C Irwin, KK Singh - Translational Psychiatry, 2023 - nature.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder caused by
genetic or environmental perturbations during early development. Diagnoses are dependent …
genetic or environmental perturbations during early development. Diagnoses are dependent …