Nausea and vomiting in 2021: a comprehensive update

M Heckroth, RT Luckett, C Moser… - Journal of clinical …, 2021 - journals.lww.com
Background: N/V are common symptoms encountered in medicine. While most cases of
acute N/V related to a specific cause can be straightforward to manage, other cases of acute …

Ghrelin and motilin receptors as drug targets for gastrointestinal disorders

GJ Sanger, JB Furness - Nature Reviews Gastroenterology & …, 2016 - nature.com
The gastrointestinal tract is the major source of the related hormones ghrelin and motilin,
which act on structurally similar G protein-coupled receptors. Nevertheless, selective …

Comparison of human and murine enteroendocrine cells by transcriptomic and peptidomic profiling

GP Roberts, P Larraufie, P Richards, RG Kay… - Diabetes, 2019 - Am Diabetes Assoc
Enteroendocrine cells (EECs) produce hormones such as glucagon-like peptide 1 and
peptide YY that regulate food absorption, insulin secretion, and appetite. Based on the …

Adolescent fatigue, POTS, and recovery: a guide for clinicians

SJ Kizilbash, SP Ahrens, BK Bruce, G Chelimsky… - Current problems in …, 2014 - Elsevier
Many teenagers who struggle with chronic fatigue have symptoms suggestive of autonomic
dysfunction that may include lightheadedness, headaches, palpitations, nausea, and …

An analysis of the pharmacological rationale for selecting drugs to inhibit vomiting or increase gastric emptying during treatment of gastroparesis

GJ Sanger, PLR Andrews - Alimentary Pharmacology & …, 2023 - Wiley Online Library
Background Drugs which can inhibit nausea/vomiting and/or increase gastric emptying are
used to treat gastroparesis, mostly 'off‐label'. Within each category, they act at different …

Cardiovascular safety of prokinetic agents: a focus on drug‐induced arrhythmias

JR Giudicessi, MJ Ackerman… - Neurogastroenterology …, 2018 - Wiley Online Library
Background Gastrointestinal sensorimotor dysfunction underlies a wide range of
esophageal, gastric, and intestinal motility and functional disorders that collectively …

Erythromycin formulations—a journey to advanced drug delivery

VM Platon, B Dragoi, L Marin - Pharmaceutics, 2022 - mdpi.com
Erythromycin (ERY) is a macrolide compound with a broad antimicrobial spectrum which is
currently being used to treat a large number of bacterial infections affecting the skin …

The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin

J Broad, GJ Sanger - British journal of pharmacology, 2013 - Wiley Online Library
Background and Purpose The antibiotic azithromycin is a suggested alternative to
erythromycin for treating patients with delayed gastric emptying. However, although …

Diabetic gastroparesis and glycaemic control

R Jalleh, CS Marathe, CK Rayner, KL Jones… - Current diabetes …, 2019 - Springer
Abstract Purpose of Review Gastroparesis is an important complication of diabetes that may
have a major impact on the quality of life as a result of upper gastrointestinal symptoms and …

Neurochemical mechanisms and pharmacologic strategies in managing nausea and vomiting related to cyclic vomiting syndrome and other gastrointestinal disorders

M Bashashati, RW McCallum - European journal of pharmacology, 2014 - Elsevier
Nausea and vomiting are common gastrointestinal complaints which could be triggered by
stimuli in both the peripheral and central nervous systems. They may be considered as …