A direct and an indirect relationship between paraoxonase 1 (PON1) and atherosclerosis
exists. Given PON1's physical location within high‐density lipoprotein (HDL) particles and its …

Background: Chronic kidney disease (CKD) is an increasingly prevalent disease state met
with great morbidity and mortality primarily resulting from the high incidence of adverse …

Polycystic ovary syndrome (PCOS) is associated with altered lipid profile and increased
small, dense LDL particles (sdLDL). Considering that paraoxonase 1 (PON1) is an …

In the general population, the ability of high-density lipoproteins (HDLs) to promote
cholesterol efflux is a predictor of cardiovascular events, independently of HDL cholesterol …

Colorectal cancer (CRC) is a highly prevalent malignancy with multifactorial etiology, which
includes metabolic alterations as contributors to disease development. Studies have shown …

Purpose Medium cut-off membranes were developed for providing increased clearance of
larger middle-molecule uremic toxins. We compared the effect of low-flux, medium cut-off …

New Findings What is the central question of this study? Can resistance training with and
without blood flow restriction improve redox balance and positively impact the autonomic …

The aim of this multicentric study was to assess the impacts of oxidative stress, inflammation,
and the presence of small, dense, low-density lipoproteins (sdLDL) on the antioxidative …

Paraoxonase-1 (PON-1) is a hydrolytic enzyme associated with HDL, contributing to its anti-
inflammatory, antioxidant, and anti-atherogenic properties. Deficiencies in PON-1 activity …

Papraoxonase-1 (PON1) is a hydrolytic lactonase enzyme that is synthesized in the liver and
circulates attached to high-density lipoproteins (HDL). Clinical studies have demonstrated …