Primary open angle glaucoma (POAG) is the most common form of glaucoma and the 2nd
most common cause of irreversible vision loss in the United States. Nearly 67 million people …

Retinal ganglion cells (RGC) bear the sole responsibility of propagating visual stimuli to the
brain. Their axons, which make up the optic nerve, project from the retina to the brain …

The conventional outflow pathway is a complex tissue responsible for maintaining
intraocular pressure (IOP) homeostasis. The coordinated effort of multiple cells with differing …

Background Fibroproliferative repair starts early in the inflammatory phase of acute
respiratory distress syndrome (ARDS) and indicates a poor prognosis. Lumican, a small …

Retinal ganglion cells (RGC) are terminally differentiated CNS neurons that possess limited
endogenous regenerative capacity after injury and thus RGC death causes permanent …

Disorganization of the transparent collagenous matrix in the cornea, as a consequence of a
variety of infections and inflammatory conditions, leads to corneal opacity and sight-loss …

Glaucoma is a chronic and progressive neurodegenerative disease characterized by the
loss of retinal ganglion cells and visual field defects, currently affecting around 1% of the …

Retinal diseases such as age-related macular degeneration (AMD), retinopathy of
prematurity (ROP), and diabetic retinopathy (DR) are the leading causes of visual …

Decorin is an archetypal member of the small leucine-rich proteoglycan gene family and is
involved in various biological functions and many signaling networks, interacting with extra …

Aberrant expression and signaling of Transforming Growth Factor (TGF)-β is strongly
associated with development of elevated intraocular pressure (IOP) and primary open-angle …