[HTML][HTML] Role of fibronectin in primary open angle glaucoma
JA Faralli, MS Filla, DM Peters - Cells, 2019 - mdpi.com
Primary open angle glaucoma (POAG) is the most common form of glaucoma and the 2nd
most common cause of irreversible vision loss in the United States. Nearly 67 million people …
most common cause of irreversible vision loss in the United States. Nearly 67 million people …
Evaluating retinal ganglion cell loss and dysfunction
B Mead, S Tomarev - Experimental eye research, 2016 - Elsevier
Retinal ganglion cells (RGC) bear the sole responsibility of propagating visual stimuli to the
brain. Their axons, which make up the optic nerve, project from the retina to the brain …
brain. Their axons, which make up the optic nerve, project from the retina to the brain …
Molecular taxonomy of human ocular outflow tissues defined by single-cell transcriptomics
G Patel, W Fury, H Yang… - Proceedings of the …, 2020 - National Acad Sciences
The conventional outflow pathway is a complex tissue responsible for maintaining
intraocular pressure (IOP) homeostasis. The coordinated effort of multiple cells with differing …
intraocular pressure (IOP) homeostasis. The coordinated effort of multiple cells with differing …
[HTML][HTML] Lumican is elevated in the lung in human and experimental acute respiratory distress syndrome and promotes early fibrotic responses to lung injury
K Wang, Y Wang, Y Cao, H Wang, Y Zhou… - Journal of translational …, 2022 - Springer
Background Fibroproliferative repair starts early in the inflammatory phase of acute
respiratory distress syndrome (ARDS) and indicates a poor prognosis. Lumican, a small …
respiratory distress syndrome (ARDS) and indicates a poor prognosis. Lumican, a small …
[HTML][HTML] Caspases in retinal ganglion cell death and axon regeneration
Retinal ganglion cells (RGC) are terminally differentiated CNS neurons that possess limited
endogenous regenerative capacity after injury and thus RGC death causes permanent …
endogenous regenerative capacity after injury and thus RGC death causes permanent …
[HTML][HTML] Sustained release of decorin to the surface of the eye enables scarless corneal regeneration
Disorganization of the transparent collagenous matrix in the cornea, as a consequence of a
variety of infections and inflammatory conditions, leads to corneal opacity and sight-loss …
variety of infections and inflammatory conditions, leads to corneal opacity and sight-loss …
[HTML][HTML] Glaucoma: Novel antifibrotic therapeutics for the trabecular meshwork
M Qin, C Yu-Wai-Man - European Journal of Pharmacology, 2023 - Elsevier
Glaucoma is a chronic and progressive neurodegenerative disease characterized by the
loss of retinal ganglion cells and visual field defects, currently affecting around 1% of the …
loss of retinal ganglion cells and visual field defects, currently affecting around 1% of the …
[HTML][HTML] Small leucine-rich proteoglycans (SLRPs) in the retina
SWY Low, TB Connor, IS Kassem… - International Journal of …, 2021 - mdpi.com
Retinal diseases such as age-related macular degeneration (AMD), retinopathy of
prematurity (ROP), and diabetic retinopathy (DR) are the leading causes of visual …
prematurity (ROP), and diabetic retinopathy (DR) are the leading causes of visual …
[HTML][HTML] Role of decorin in the lens and ocular diseases
E Kubo, S Shibata, T Shibata, H Sasaki, DP Singh - Cells, 2022 - mdpi.com
Decorin is an archetypal member of the small leucine-rich proteoglycan gene family and is
involved in various biological functions and many signaling networks, interacting with extra …
involved in various biological functions and many signaling networks, interacting with extra …
Smad-independent TGF-β2 signaling pathways in human trabecular meshwork cells
CL Pervan - Experimental eye research, 2017 - Elsevier
Aberrant expression and signaling of Transforming Growth Factor (TGF)-β is strongly
associated with development of elevated intraocular pressure (IOP) and primary open-angle …
associated with development of elevated intraocular pressure (IOP) and primary open-angle …